Results 41 to 50 of about 61,670 (295)
Identification and functional analysis of a novel von Willebrand factor mutation in a family with type 2A von Willebrand disease. [PDF]
PLoS ONE, 2012 von Willebrand factor (VWF) is essential for normal hemostasis. VWF gene mutations cause the hemorrhagic von Willebrand disease (VWD). In this study, a 9-year-old boy was diagnosed as type 2A VWD, based on a history of abnormal bleeding, low plasma VWF ...
Jing Dong +7 more
doaj +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Calculated VWF excess and VWF half-life in pregnancy.
, 2014 Calculated VWF excess and VWF half-life in pregnancy.
Gayle T. Teramura (698015) +7 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian +6 more
wiley +1 more source
Clinical and Applied Thrombosis/Hemostasis, 2020 von Willebrand factor (VWF) acts as a bridge between platelets and the subendothelial matrix following vessel damage and plays a vital role in coronary artery disease (CAD).
Bin Yan MS +8 more
doaj +1 more source
Angiogenesis and the ADAMTS13-VWF balance [PDF]
Blood, 2017 In this issue of Blood , Xu et al describe a new function for the metalloprotease ADAMTS13 in blood vessel formation following brain ischemia. Using multiple approaches in mice, they show that ADAMTS13 is required for neovascularization and vascular repair following ischemic stroke.
openaire +2 more sources
Hybrid Biofabrication of a Hierarchically Organized Periosteum‐Inspired In Vitro Platform
Advanced Healthcare Materials, EarlyView.A hybrid biofabrication strategy integrates melt electrowriting with extrusion‐based 3D bioprinting to create a hierarchically organized periosteum‐inspired in vitro platform. Spatially defined osteogenic, fibrous, and endothelial cell‐containing compartments support long‐term culture, osteogenic maturation, and CD31+ endothelial cell organization ...
Yakui Liu +7 more
wiley +1 more source
Advanced Science, EarlyView.Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen +20 more
wiley +1 more source
On the issue of recurrent thrombosis in cancer patients
Акушерство, гинекология и репродукцияAim: to identify the key pathogenic factors and triggers associated with recurrent venous thromboembolic events (VTE) in gynaecological oncology patients.Materials and Methods.
K. N. Grigoreva +13 more
doaj +1 more source
Advanced Science, EarlyView.STWave transforms massive microscopic‐resolution spatial transcriptomics into interpretable fine‐scale tissue maps through patch‐wise inference, wavelet‐based multi‐scale encoding, and dual‐domain reconstruction. It reduces noise while preserving weak spatial signals, enabling efficient analysis of 6 40 000 spots of 2.47 GB GPU memory and revealing ...
Tao Jiang +9 more
wiley +1 more source