Results 181 to 190 of about 17,893 (237)

The XX Factor in Hemophilia: Diagnostic, Therapeutic, and Research Gaps for Women and Girls

Haemophilia, Volume 32, Issue 6, Page 1481-1487, November/December 2026.
ABSTRACT Introduction Hemophilia has traditionally been viewed as an X‐linked disorder affecting men and boys, with women and girls labeled as “carriers”, presumed to be clinically unaffected. This paradigm has contributed to under‐recognition, delayed diagnosis, and undertreatment of females with hemophilia‐associated genotypes despite an increasingly
Kelsey Uminski, Ellen Cusano
wiley   +1 more source

Proteomic Analysis of Serum Extracellular Vesicles Revealed Fibulin‐3 as a Novel Predictive Biomarker for Hepatocellular Carcinoma in Patients With Chronic Hepatitis B

Hepatology Research, Volume 56, Issue 11, Page 1614-1631, November 2026.
We carried out proteomic analysis of serum extracellular vesicles to identify biomarkers predictive of hepatocellular carcinoma (HCC) development in patients with chronic hepatitis B receiving nucleos(t)ide analog therapy. Candidate proteins identified through proteomic analysis were subsequently quantified in serum by ELISA.
Emi Sometani, Kazuhiro Murai, Hayato Hikita, Jihyun Sung, Satoshi Muraoka, Hidenori Toyoda, Satoshi Tanaka, Takayuki Miyake, Shinji Kuriki, Kenji Fukumoto, Satoshi Shigeno, Yuta Myojin, Kazuki Maesaka, Kumiko Shirai, Yuki Makino, Yuki Tahata, Yoshinobu Saito, Takahiro Kodama, Ryotaro Sakamori, Jun Adachi, Tomomi Yamada, Tetsuo Takehara   +21 more
wiley   +1 more source

Recombinant ADAMTS13 Ameliorates Liver Injury and Improves Hepatic Microcirculation in a Murine Acute‐on‐Chronic Liver Failure Model

Hepatology Research, Volume 56, Issue 11, Page 1737-1748, November 2026.
ABSTRACT Aim The therapeutic significance of recombinant a disintegrin‐like and metalloprotease with thrombospondin type 1 motif 13 (rADAMTS13) in acute‐on‐chronic liver failure (ACLF) remains unclear. We aimed to investigate the therapeutic effects of rADAMTS13 in a murine model of ACLF‐like liver injury.
Jun‐ichi Hanatani, Norihisa Nishimura, Kosuke Kaji, Masayoshi Takami, Hiroyuki Masuda, Hiroaki Takaya, Koh Kitagawa, Shinya Sato, Tadashi Namisaki, Hitoshi Yoshiji   +9 more
wiley   +1 more source

Blood‐ and Liver Stiffness‐Based Non‐Invasive Tests for Clinically Significant Portal Hypertension in Patients With cACLD and HCC

Liver International, Volume 46, Issue 11, November 2026.
ABSTRACT Background and Aims The applicability of non‐invasive tests (NITs) for clinically significant portal hypertension (CSPH) in patients with hepatocellular carcinoma (HCC) is controversial. We performed a head‐to‐head comparison of various NITs for CSPH and evaluated rule‐in/‐out criteria.
Lorenz Balcar, Tina Jasmin Haunold, Mathias Jachs, Georg Semmler, Benedikt Simbrunner, Albert Friedrich Stättermayer, David Pereyra, Christoph Schwarz, Stefan Stremitzer, Klaus Kaczirek, Patrick Starlinger, Peter Quehenberger, Michael Trauner, Bernhard Scheiner, Thomas Reiberger, Matthias Pinter, Mattias Mandorfer   +16 more
wiley   +1 more source

[vWF-cleaving protease/ADAMTS 13].

[Rinsho ketsueki] The Japanese journal of clinical hematology, 2003
Masanori, Matsumoto, Hideo, Yagi, Yoshihiro, Fujimura   +2 more
openaire   +2 more sources

Clinical Outcomes of Efanesoctocog Alfa Prophylaxis in Children With Severe Haemophilia A: Interim Data From XTEND‐ed

Haemophilia, Volume 32, Issue 6, Page 1535-1539, November/December 2026.
Lynn Malec, Beatrice Nolan, Anthony K C Chan, Manuela Albisetti, Sheng‐Chieh Chou, Bulent Zulfikar, Mindy Simpson, Liqi Feng, Helena Palmborg, Graham Neill, Lydia Abad‐Franch, Sriya Gunawardena, Karin Fijnvandraat   +12 more
wiley   +1 more source

A NAC for Reducing vWF

The Hematologist, 2011
openaire   +1 more source

The need for dried plasma—Still a national issue: Where are we and recommendations

Transfusion, Volume 66, Issue 11, Page 2441-2449, November 2026.
Anthony E. Pusateri, Shibani Pati, Toby A. Silverman, Roman Dudaryk, Joseph F. Rappold, Lisa Buckley, Andrew P. Cap, Jose A. Cancelas, Laurence M. Corash, G. Michael Fitzpatrick, Michael Ganio, Adam Gerber, Richard Gonzales, Jennifer M. Gurney, Ernest E. Moore, Hunter B. Moore, Vijayan Nair, Michael Policastro, Travis M. Polk, Jeffrey W. Shupp, Jason L. Sperry, Ralph R. Vassallo, Therese A. West, John B. Holcomb, Lester Martinez‐Lopez   +24 more
wiley   +1 more source

Uptake of vWF–Anti-vWF Complexes by Platelets in Suspension

Arteriosclerosis, Thrombosis, and Vascular Biology, 1996
Efforts to identify the translocation of glycoprotein (GP) Ib/IX receptors, either bound to von Willebrand factor (vWF) or not, from exposed surfaces to interior membranes of thrombin-activated platelets in suspension have been unsuccessful. To observe vWF uptake by platelets, we added an anti-vWF antibody and staphylococcal protein A–gold (to act as a
Gines Escolar, M D Krumwiede, J G White
exaly   +4 more sources

Sequence Alignment between vWF and Peptides Inhibiting the vWF-collagen Interaction Does not Result in the Identification of a Collagen-binding Site in vWF

Thrombosis and Haemostasis, 2000
SummaryWe previously found that two peptides (N- and Q-peptide) selected by phage display for binding to an anti-vWF antibody, were able to inhibit vWF-binding to collagen (1). The sequence of those peptides could be aligned with the sequence in vWF at position 1129-1136 just outside the A3-domain.
Vanhoorelbeke, K., van der Plas, R.M., Vandecasteele, G., Vauterin, S., Huizinga, E.G., Sixma, J.J., Deckmijn, H.   +6 more
openaire   +4 more sources