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Unclear-onset stroke: Daytime-unwitnessed stroke vs. wake-up stroke
International Journal of Stroke, 2016Background and purpose The onset of wake-up stroke and daytime-unwitnessed stroke is unclear. Though the clinical importance is similar by both being excluded from reperfusion therapy, the characteristics of daytime-unwitnessed stroke are less known than that of wake-up stroke.
Yeon-Jung, Kim +4 more
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Abstract Traditionally, wake-up strokes were considered unamenable to any acute intervention. However, endovascular retrieval of large-vessel occlusive disease remains an option in many patients who awaken with a major neurologic deficit from an evolving ischemic stroke.
Eelco F.M. Wijdicks +1 more
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Eelco F.M. Wijdicks +1 more
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Advancements in Imaging for the Diagnosis of Wake-up Stroke
The NeurologistBackground: The concept of wake-up stroke (WUS) as a distinct subtype of acute ischaemic stroke, characterized by an uncertain onset time, traditionally resulted in the exclusion of patients from intravenous thrombolysis treatment.
Yang, Li, Chun-Hui, Ma
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Clinical Effect of Thrombolysis in Wake-Up Stroke Compared to Non-Wake-Up Stroke
Journal of Neurology Research Review & ReportsBackground and Aims: In known onset stroke (KOS) cerebral CT is performed to select patients eligible for intravenous thrombolysis (IVT) while MRI (DWI-FLAIR) mismatch aids selection of patients in wake-up stroke (WUPS). In this study, the clinical outcome and safety profile of IVT in WUPS patients is compared to KOS patients. Methods: IVT treated WUPS
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Differences in Wake-up and Unknown Onset Stroke Examined in a Stroke Registry
International Journal of Stroke, 2014Introduction Debate exists as to whether wake-up stroke (WUS) (i.e. symptoms first noted on waking) differs from stroke developing while awake [awake onset stroke (AOS)]. Unknown onset stroke (UOS) with unclear symptom onset time is infrequently studied.
John M, Reid +6 more
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Obstructive sleep apnea linked to wake-up strokes
Journal of Neurology, 2012Obstructive sleep apnea (OSA) has been considered as one of the risk factors for ischemic stroke, but the impact of OSA on wake-up stroke (WUS) is not well studied. We aimed to determine the relationship between OSA and WUS. We prospectively recruited 71 patients with mild to moderate ischemic stroke during hospitalization.
Sun-Wung, Hsieh +4 more
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Pathophysiologic mechanisms, neuroimaging and treatment in wake-up stroke
CNS Spectrums, 2019AbstractWake-up stroke (WUS) or ischemic stroke occurring during sleep accounts for 14%–29.6% of all ischemic strokes. Management of WUS is complicated by its narrow therapeutic time window and attributable risk factors, which can affect the safety and efficacy of administering intravenous (IV) tissue plasminogen activator (t-PA).
Mohamed Elfil +5 more
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Recanalization therapies for wake‐up stroke
International Journal of Nursing Practice, 2020Charlotte, Millard +2 more
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Thrombolysis in wake-up stroke based on MRI mismatch
Journal of the Neurological SciencesWake-up stroke (WUPS) patients can be selected to intravenous thrombolysis (IVT) treatment based on the Magnetic Resonance Imaging (MRI) mismatch concept. However, recent studies suggest the introduction of modified MRI mismatch criteria, allowing IVT in WUPS patients with a partial mismatch.WUPS patients treated with IVT in the NOR-TEST trial and ...
Hassan Khan, Ahmed +6 more
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