Results 11 to 20 of about 8,636,999 (167)

Surrogate biomarkers of outcome for wake-up ischemic stroke

BMC Neurology, 2022
Background Wake-up ischemic stroke (IS) has been usually excluded from acute stroke therapy options for being outside of the safe treatment window. We identified risk factors, and clinical or molecular biomarkers that could be therapeutic targets for ...
Pablo Hervella, María Luz Alonso-Alonso, María Pérez-Mato, Manuel Rodríguez-Yáñez, Susana Arias-Rivas, Iria López-Dequidt, José M. Pumar, Tomás Sobrino, Francisco Campos, José Castillo, Ramón Iglesias-Rey   +10 more
doaj   +6 more sources

Wake-up stroke and unknown-onset stroke; occurrence and characteristics from the nationwide Norwegian Stroke Register [PDF]

European Stroke Journal, 2022
INTRODUCTION: Population-based knowledge of the characteristics of wake-up stroke and unknown-onset stroke is limited. We compared occurrence and characteristics of ischaemic and haemorrhagic wake-up stroke, unknown-onset stroke and known-onset stroke in
Arnstein Tveiten, Ellisiv Mathiesen, Bent Indredavik   +2 more
exaly   +4 more sources

Wake-up stroke: clinical characteristics, imaging findings, and treatment option – an update. [PDF]

Frontiers in Neurology, 2014
About 25% of all strokes occur during sleep, i.e. without knowledge of exact time of symptom onset. According to licensing criteria, this large group of patients is excluded from treatment with rt-PA, the only specific stroke treatment proven effective ...
David eRimmele, Götz eThomalla
doaj   +4 more sources

Supine blood pressure normalised by daytime series values is independently associated with ischaemic wake-up stroke

Blood Pressure, 2022
Purpose Wake-up stroke constitutes up to 1/4 of all ischaemic strokes; however, its pathomechanisms remain largely unknown. Although low nocturnal blood flow may be the underlying cause, little is known about blood pressure (BP) characteristic of wake-up
Kamil Kowalczyk, Mariusz Kwarciany, Krzysztof Narkiewicz, Bartosz Karaszewski, Dariusz Gąsecki   +4 more
doaj   +3 more sources

Evaluation of stroke related risk factors in wake up and non-wake up stroke patients

Emergency Care Journal, 2020
Wake-Up Stroke (WUS) is defined as a stroke with the unclear onset of symptoms and subsequent neurological deficits which perceived upon awakening. WUS patients are often excluded from acute fibrinolytic and reperfusion therapy due to the unknown exact ...
Elyar Sadeghi-Hokmabadi, Samad Shams Vahdati, Reza Rikhtegar, Nazila Karzad, Aysa Rezabakhsh   +4 more
doaj   +3 more sources

Safety and efficacy of intravenous thrombolysis in stroke patients on prior antiplatelet therapy in the WAKE-UP trial

Neurological Research and Practice, 2020
Background One quarter to one third of patients eligible for systemic thrombolysis are on antiplatelet therapy at presentation. In this study, we aimed to assess the safety and efficacy of intravenous thrombolysis in stroke patients on prescribed ...
Benedikt M. Frey, Florent Boutitie, Bastian Cheng, Tae-Hee Cho, Martin Ebinger, Matthias Endres, Jochen B. Fiebach, Jens Fiehler, Ian Ford, Ivana Galinovic, Alina Königsberg, Josep Puig, Pascal Roy, Anke Wouters, Tim Magnus, Vincent Thijs, Robin Lemmens, Keith W. Muir, Norbert Nighoghossian, Salvador Pedraza, Claus Z. Simonsen, Christian Gerloff, Götz Thomalla, on behalf of the WAKE-UP investigators   +23 more
doaj   +2 more sources

Clinical Characteristics and Outcome of Patients With Hemorrhagic Transformation After Intravenous Thrombolysis in the WAKE-UP Trial

Frontiers in Neurology, 2020
Background: Hemorrhagic transformation (HT) is an important complication of intravenous thrombolysis with alteplase. HT can show a wide range from petechiae to parenchymal hematoma with mass effect with varying clinical impact.
Märit Jensen, Eckhard Schlemm, Bastian Cheng, Iris Lettow, Fanny Quandt, Florent Boutitie, Florent Boutitie, Florent Boutitie, Martin Ebinger, Martin Ebinger, Matthias Endres, Matthias Endres, Matthias Endres, Matthias Endres, Jochen B. Fiebach, Jens Fiehler, Ivana Galinovic, Vincent Thijs, Vincent Thijs, Robin Lemmens, Robin Lemmens, Robin Lemmens, Keith W. Muir, Norbert Nighoghossian, Salvador Pedraza, Claus Z. Simonsen, Christian Gerloff, Götz Thomalla   +27 more
doaj   +2 more sources

Wake-up stroke is not associated with obstructive sleep apnea. [PDF]

Sleep Med, 2021
Obstructive sleep apnea is a risk factor for stroke. This study sought to assess the relationship between obstructive sleep apnea (OSA) and wake-up strokes (WUS), that is, stroke symptoms that are first noted upon awakening from sleep.In this analysis, 837 Brain Attack Surveillance in Corpus Christi (BASIC) project participants completed an interview ...
Schütz SG, Lisabeth LD, Gibbs R, Shi X, Case E, Chervin RD, Brown DL.   +6 more
europepmc   +3 more sources

Wake-Up Stroke: Clinical and Neuroimaging Characteristics [PDF]

Cerebrovascular Diseases, 2010
<i>Background:</i> Approximately 25% of ischemic stroke patients awaken with neurological deficits. In these patients, in whom the time from symptom onset is uncertain, brain imaging is a potential strategy to characterize the ischemia duration and the presence of salvageable brain tissue.
Gisele S, Silva, Fabricio O, Lima, Erica C S, Camargo, Wade S, Smith, Aneesh B, Singhal, David M, Greer, Hakan, Ay, Michael H, Lev, Gordon J, Harris, Elkan F, Halpern, Shruti, Sonni, Walter, Koroshetz, Karen L, Furie   +12 more
openaire   +3 more sources

Rise and restore: the role of cerebral angiogram with mechanical thrombectomy in the case of cerebral vascular accident and a wake-up stroke: a case report [PDF]

Journal of Medical Case Reports
Background Intravenous thrombolytic therapy with tissue plasminogen activators (that is, tenecteplase, alteplase) and mechanical thrombectomy are both considered standard treatments for acute ischemic stroke, with mechanical thrombectomy being the gold ...
Suha Moten, Maeve Tremis, Fill-Bryan, Harish Shownkeen   +3 more
doaj   +2 more sources