Results 141 to 150 of about 357,503 (297)
BMC GeriatricsBackground Due to the impact of COVID-19, telehealth technologies have become crucial for managing the health of community-dwelling older adults with frailty.
Pei-Shan Li +7 more
doaj +1 more source
Heteroskedasticity Testing Through Comparison of Wald-Type Statistics [PDF]
A test for heteroskedasticity within the context of classical linear regression can be based on the difference between Wald statistics in heteroskedasticity-robust and nonrobust forms.
Esmeralda Ramalho +2 more
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Multimorbidity and Associations with Cognition and Alzheimer's Disease Biomarkers
Annals of Neurology, EarlyView.Objective Multimorbidity, the coexistence of 2 or more chronic conditions, has been linked to cognitive aging and Alzheimer's disease (AD) and AD‐related dementias, yet the mechanisms remain unclear. We aimed to examine the associations of multimorbidity with cognition and biomarkers across multiple mechanistic pathways.
Xiaqing Jiang +45 more
wiley +1 more source
Beyond PEGylation: Archaeal Lipids for Long‐Circulating Liposomes
Advanced NanoBiomed Research, EarlyView.Archaeal lipid‐based liposomes, particularly those containing caldarchaeol (GDGT), were found to significantly prolong the circulation time of vancomycin in rats, matching the pharmacokinetic properties of PEGylated systems. These findings suggest archaeal lipids as promising non‐PEG excipients for parenteral applications to minimize drug clearance ...
Viktor Sedlmayr +9 more
wiley +1 more source
Sieve Inference on Semi-nonparametric Time Series Models [PDF]
The method of sieves has been widely used in estimating semiparametric and nonparametric models. In this paper, we first provide a general theory on the asymptotic normality of plug-in sieve M estimators of possibly irregular functionals of semi ...
Xiaohong Chen, Yixiao Sun, Zhipeng Liao
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Arthritis &Rheumatology, EarlyView.Objective The multinational, phase 3, double‐blind, placebo‐controlled TULIP‐SC trial evaluated the efficacy and safety of subcutaneous anifrolumab in adults who have moderate to severe systemic lupus erythematosus (SLE) activity, despite receiving standard therapy. Methods Adults with SLE received subcutaneous anifrolumab 120 mg or placebo once weekly
Susan Manzi +12 more
wiley +1 more source
Late‐Onset Rheumatoid Arthritis and Air Pollution in the Multiethnic Cohort
Arthritis &Rheumatology, EarlyView.Objective To evaluate the effects of ambient air pollution on rheumatoid arthritis (RA) incidence in a racially and ethnically diverse population. Methods This analysis included 42,152 California Multiethnic Cohort participants, aged ≥65 years (>70% African American and Latino adults) who were enrolled in the Fee For Service component of Medicare (2001–
Anna H. Wu +14 more
wiley +1 more source
Hypothesis testing and sample size considerations for the test-negative design
BMC Medical Research MethodologyThe test-negative design (TND) is an observational study design to evaluate vaccine effectiveness (VE) that enrolls individuals receiving diagnostic testing for a target disease as part of routine care.
Yanan Huo +4 more
doaj +1 more source
Arthritis &Rheumatology, EarlyView.Objective To assess the association between early antimalarial adherence and future acute care utilization and cost in a population‐based cohort of incident rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Methods All patients with incident RA/SLE and new antimalarial use in British Columbia, Canada, between January 1997 and March 2022
Md Rashedul Hoque +7 more
wiley +1 more source
Simple Wald tests of the fractional integration parameter : an overview of new results [PDF]
This paper presents an overview of some new results regarding an easily implementable Wald test-statistic (EFDF test) of the null hypotheses that a time-series process is I(1) or I(0) against fractional I(d) alternatives, with d?(0,1), allowing for ...
Jesus Gonzalo +2 more
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