Results 31 to 40 of about 357,503 (297)
Validating attribute hierarchies in cognitive diagnosis models
Frontiers in PsychologyCognitive diagnosis models (CDMs) are restricted latent class models that are widely used in educational and psychological fields. Attribute hierarchy, as an important structural feature of the CDM, can provide critical information for inferring ...
Xueqin Zhang +3 more
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Genetic association tests in family samples for multi-category phenotypes
BMC Genomics, 2021 Background Advancements in statistical methods and sequencing technology have led to numerous novel discoveries in human genetics in the past two decades.
Shuai Wang +2 more
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Statistical Inference for Odds Ratio of Two Proportions in Bilateral Correlated Data
Axioms, 2022 Bilateral correlated data frequently arise in medical clinical studies such as otolaryngology and ophthalmology. Based on an equal correlation coefficient model, this paper mainly aimed to investigate the statistical inference for the odds ratio of two ...
Zhiming Li, Changxing Ma
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Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
The Implication of Wald Test Anchor-All-Test-All Procedure for Anchor Selection
دراسات: العلوم التربوية, 2021 This study aims to provide information on whether the more practical and time saver anchor-all-test-all procedure (AATA) strategy for anchor selection can demonstrate similar performance or outperform the well known all-others-as-anchors (AOAA ...
Yahia Alsmadi
doaj
Frontiers in Psychology, 2022 Within the framework of constrained statistical inference, we can test informative hypotheses, in which, for example, regression coefficients are constrained to have a certain direction or be in a specific order. A large amount of frequentist informative
Caroline Keck, Axel Mayer, Yves Rosseel
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Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source