Results 101 to 110 of about 315,901 (259)

Inhibition of the RNA Regulator HuR Mitigates Spinal Cord Injury by Potently Suppressing Post‐Injury Neuroinflammation

The FASEB Journal, Volume 39, Issue 9, 15 May 2025.
Delivery of SRI‐42127 after spinal cord injury blocks HuR nucleocytoplasmic translocation in microglia and astrocytes to suppress key neuroinflammatory mediators at the site of injury including, IL‐1β, IL‐6, TNF‐α, COX‐2, INOS, and CCL2. In parallel, there is a reduction of peripheral inflammatory responses in the spleen, liver, and circulation.
Mohammed Amir Husain, Reed Smith, Robert E. Sorge, Abdulraheem Kaimari, Ying Si, Ali Z. Hassan, Abhishek Guha, Katherine A. Smith, Christopher P. Cardozo, Jennifer J. DeBerry, Shaida A. Andrabi, L. Burt Nabors, Natalia Filippova, Caroline K. Webb, Peter H. King   +14 more
wiley   +1 more source

On generalized degenerate Euler-Genocchi polynomials [PDF]

arXiv, 2022
We introduce the generalized degenerate Euler-Genocchi polynomials as a degenerate version of the Euler-Genocchi polynomials. In addition, we introduce their higher-order version, namely the generalized degenerate Euler-Genocchi polynomials of order {\alpha}, as a degenerate version of the generalized Euler-Genocchi polynomials of order {\alpha}.
arxiv  

Clinical Relevance of ‘Cap’ and ‘Track’ Development after Recent Small Subcortical Infarct

Annals of Neurology, Volume 97, Issue 5, Page 942-955, May 2025.
Objective After a recent small subcortical infarct (RSSI), some patients develop perilesional or remote hyperintensities (‘caps/tracks’) to the index infarct on T2/FLAIR MRI. However, their clinical relevance remains unclear. We investigated the clinicoradiological correlates of ‘caps/tracks’, and their impact on long‐term outcomes following RSSI ...
Yajun Cheng, Carmen Arteaga‐Reyes, Una Clancy, Daniela Jaime Garcia, Maria Del C. Valdés Hernández, Michael J. Thrippleton, Michael S. Stringer, Gordon W. Blair, Stewart Wiseman, Francesca M. Chappell, Junfang Zhang, Xiaodi Liu, Angela C.C. Jochems, Susana Muñoz Maniega, Eleni Sakka, Mark E. Bastin, Rosalind Brown, Caroline M.J. Loos, Stephen D.J. Makin, Ming Liu, Bo Wu, Fergus N. Doubal, Joanna M. Wardlaw, MSS‐2, MSS‐3 and the INVESTIGATE‐SVDs Study Group, Ian Marshall, Olivia K.L. Hamilton, Ellen Backhouse, Will Hewins, Rachel Locherty, Emilie Sleight, Alasdair G. Morgan, Cameron Manning, Iona Hamilton, Gayle Barclay, Donna McIntyre, Charlotte Jardine, Dominic Job, David Perry, Tom MacGillivray, Charlene Hamid, Martin Dichgans, Anna Kopczak, Marco Duering, Benno Gesierich, Karin Waegemann, Michael Ingrisch, Salvatore Rudilosso, Ernest Chui, Esther Janssen, Robert J van Oostenbrugge, Julie Staals, Maud van Dinther, Danielle Kerkhofs, Walter H Backes, Geert Jan Biessels, Hilde van den Brink, Laurien P Onkenhout, Tine Arts, Stanley DT Pham, Jeroen Hendrikse, Jaco JMZ Zwanenburg, Jeroen CW Siero, Alastair JS Webb   +63 more
wiley   +1 more source

Early myelin breakdown following sural nerve crush: a freeze-fracture study

Brazilian Journal of Medical and Biological Research, 2000
In this study we describe the early changes of the myelin sheath following surgical nerve crush. We used the freeze-fracture technique to better evaluate myelin alterations during an early stage of Wallerian degeneration.
A.M.B. Martinez, S. Canavarro
doaj   +1 more source

MRI findings in a case of spinal cord Wallerian degeneration following trauma

Neurosciences, 2016
Wallerian degeneration is a well-known entity which represents distal axonal degeneration and myelin disintegration following interruption of any axon from its cellular connection.
P. Mittal, Ranjana Gupta, A. Mittal, Kapish Mittal   +3 more
semanticscholar   +1 more source

Occupational nerve injuries

Muscle &Nerve, Volume 71, Issue 5, Page 732-746, May 2025.
Abstract Occupational nerve injuries span a broad array of pathologies and contribute toward functional limitation, disability, and economic impact. Early and accurate recognition, treatment, and management of workplace factors rely on a thorough understanding of the anatomic and biomechanical factors that drive nerve injury.
Sandra L. Hearn, Shawn P. Jorgensen, Joelle M. Gabet, Gregory T. Carter   +3 more
wiley   +1 more source

Assessment, management, and rehabilitation of traumatic peripheral nerve injuries for non‐surgeons

Muscle &Nerve, Volume 71, Issue 5, Page 696-714, May 2025.
Abstract Electrodiagnostic evaluation is often requested for persons with peripheral nerve injuries and plays an important role in their diagnosis, prognosis, and management. Peripheral nerve injuries are common and can have devastating effects on patients' physical, psychological, and socioeconomic well‐being; alongside surgeons, electrodiagnostic ...
Emma A. Bateman, Stahs Pripotnev, Juliana Larocerie‐Salgado, Douglas C. Ross, Thomas A. Miller   +4 more
wiley   +1 more source

Retrograde trans-synaptic degeneration of visual pathway in an adult with head injury

Kerala Journal of Ophthalmology, 2016
A 41-year-old male with a history of head injury 16 years previously but no visual deficit, presented with reading difficulty. Examination showed disc pallor bilaterally, and perimetry showed the left homonymous hemianopsia.
Thomas Arun Varghese, Annamma James, Cigia Paul   +2 more
doaj   +1 more source

An axiomatic approach for degenerations in triangulated categories [PDF]

arXiv, 2015
We generalise Yoshino's definition of a degeneration of two Cohen Macaulay modules to a definition of degeneration between two objects in a triangulated category. We derive some natural properties for the triangulated category and the degeneration under which the Yoshino-style degeneration is equivalent to the degeneration defined by a specific ...
arxiv  

Electrodiagnostic Assessment of Peri‐Procedural Iatrogenic Peripheral Nerve Injuries and Rehabilitation

Muscle &Nerve, Volume 71, Issue 5, Page 747-767, May 2025.
ABSTRACT Iatrogenic nerve injuries are a significant concern for medical professionals and the patients affected. Peri‐procedural nerve injuries result in functional deficits associated with pain and disability. The exact pathophysiology and etiology of peri‐procedural nerve injuries are complex and often elude providers.
Geoffrey K. Seidel, Amber R. Vocelle, Ian S. Ackers, Kenneth A. Scott, Curtis A. Carl, Barent A. G. Bradt, Daniel Dumitru, Michael T. Andary   +7 more
wiley   +1 more source