Results 91 to 100 of about 502,531 (307)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
An Alternative Public Health Vision for a National Drug Strategy: Treatment Works [PDF]
, 1991 This article returns to a war waged virtually throughout this century--a war between the theories of punishment and rehabilitation in curtailing the drug epidemic. Today, the terms of the war are recast as supply-side policies based upon law enforcement;
Gostin, Lawrence O.
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Do Filipinos Really Hate Duterte’s Leadership? Uncovering Duterte Controversies in the Philippines
Journal of Asian Social Science ResearchThis article investigates whether Filipinos genuinely have negative feelings about President Duterte’s leadership. It examines public opinions through surveys, media discussions, and actions in socio-political groups.
Givheart Dano
doaj +1 more source
The Need for New Approaches to Organised Crime in West Africa [PDF]
, 2012 LSE’s Sasha Jesperson argues that international organisations will need to vary their strategy in the war on drugs if they are to gain ground on adaptable narco ...
Jesperson, Sasha
core
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
On President Rodrigo Duterte’s “War On Drugs”: Its Impact on Philippine-China Relations [PDF]
Contemporary Chinese Political Economy and Strategic Relations: An International Journal, 2019 This study looks into the “War on Drugs” of the Duterte Administration and how it impacts on the diplomatic relations between the Philippines and China.
Diosdado B. Lopega
doaj
A “Dubious Distinction”: New Jersey’s Drug-Free School Zones & Disparately Impacted Minority Communities [PDF]
, 2014 Richard Nixon fundamentally changed the prison system in America when he launched the “War on Drugs” in 1969, leading to a series of federal laws imposing harsh mandatory sentences on drug offenders.
Overman, Taylor R.
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