Results 81 to 90 of about 502,644 (306)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Challenges, Cooperation and Paradoxes in the Coca Cocaine Complex
Politikon, 2013 The coca-cocaine complex in South America is one of the most serious threats to the region’s political, economic and social institutions. It has infected the public and private sectors with the virus of corruption and violence, and it has brought about ...
Mariá de Los Ángeles Lasa
doaj +1 more source
Academic Medicine, 1995 Most medical colleges, teaching hospitals, and other health education and treatment institutions are already expanding their horizons to include attention to the public health needs of their communities. But one pressing public health problem--substance abuse--that should be treated as a disease and handled by doctors and nurses is at present entrusted
openaire +3 more sources
The War Against Drug Producers [PDF]
This paper develops a model of a war against the producers of illegal hard drugs. This war occurs on two fronts. First, to prevent the cultivation of crops that are the raw material for producing drugs the state engages the drug producers in conflict ...
Daniel Mejia, Herschel I. Grossman
core
The introduction of diagnostic and treatment innovations for syphilis in postwar VD policy : «L'expérience belge» [PDF]
, 2004 In this article, the introduction of the Wassermann Test and arsenic-based drugs in Belgian post-war venereal disease (VD) policy is discussed (for the period 1900-1930).
Neefs, Hans
core +2 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The War on Drugs is Counterproductive, Once Again
Lecturas de Economía, 2009 Un modelo bisectorial de equilibrio general, que incluía las drogas como bienes básicos, fue relativamente exitoso para explicar el desperdicio de recursos que genera una guerra contra las drogas (Ortiz, 2003).
Carlos Humberto Ortiz
doaj +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source