Results 91 to 100 of about 167,167 (358)
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
The Non-Ideal Organic Electrochemical Transistors Impedance [PDF]
, 2019 Organic electrochemical transistors offer powerful functionalities for biosensors and neuroinspired electronics, with still much to understand on the time dependent behavior of this electrochemical device.
Crljen, Željko +4 more
core +2 more sources
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
Aby Warburg and “his masks”: images as “science without a name” [PDF]
, 2016 El artículo analiza, a partir del Ritual de la Serpiente de Aby Warburg, algunas de las líneas fundamentales de su concepción sobre la imagen como “ciencia sin nombre”.
Silva Echeto, Víctor
core
Electromechanical Probing of Ionic Currents in Energy Storage Materials
, 2010 The electrochemical processes in energy storage materials are generally linked with changes of molar volume of the host compound. Here, the frequency dependent strain response of 1D electrochemically active systems to periodic electric bias is analyzed ...
A. N. Morozovska +3 more
core +1 more source
Bayesian Triplet Loss: Uncertainty Quantification in Image Retrieval [PDF]
2021 ICCV, 2020 Uncertainty quantification in image retrieval is crucial for downstream decisions, yet it remains a challenging and largely unexplored problem. Current methods for estimating uncertainties are poorly calibrated, computationally expensive, or based on heuristics.
arxiv
Bayesian Metric Learning for Uncertainty Quantification in Image Retrieval [PDF]
arXiv, 2023 We propose the first Bayesian encoder for metric learning. Rather than relying on neural amortization as done in prior works, we learn a distribution over the network weights with the Laplace Approximation. We actualize this by first proving that the contrastive loss is a valid log-posterior.
arxiv
Variations of petrophysical properties and spectral induced polarization in response to drainage and imbibition: a study on a correlated random tube network [PDF]
Geophysical Journal International (2017) ggx474, 2017 We implement a procedure to simulate the drainage and imbibition in random, two-dimensional, square networks. We compute the resistivity index, the relative permeability, and the characteristic lengths of a correlated network at various saturation states, under the assumption that the surface conductivity can be neglected.
arxiv +1 more source
FEBS Open Bio, EarlyView.In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna +4 more
wiley +1 more source
Nature Metabolism, 2021 Pharmacological activation of the glycolytic enzyme PKM2 or expression of the constitutively active PKM1 isoform in cancer cells results in decreased lactate production, a phenomenon known as the PKM2 paradox in the Warburg effect.
Elizabeth K. Wiese +9 more
semanticscholar +1 more source