Results 1 to 10 of about 53,264 (296)

Expression of proteins associated with the Warburg‐effect and survival in colorectal cancer

open access: yesThe Journal of Pathology: Clinical Research, 2022
Previous research has suggested that the expression of proteins related to the Warburg effect may have prognostic value in colorectal cancer (CRC), but results remain inconsistent.
Kelly Offermans   +9 more
doaj   +2 more sources

Targeting the Warburg effect: A revisited perspective from molecular mechanisms to traditional and innovative therapeutic strategies in cancer

open access: yesActa Pharmaceutica Sinica B
Cancer reprogramming is an important facilitator of cancer development and survival, with tumor cells exhibiting a preference for aerobic glycolysis beyond oxidative phosphorylation, even under sufficient oxygen supply condition.
Minru Liao, Dahong Yao, Zhiwen Wang
exaly   +3 more sources

Vitamin D promotes apoptosis and enhances cisplatin sensitivity in bladder cancer cells by inhibiting the Warburg effect through the AKT/mTOR pathway [PDF]

open access: yesBMC Urology
Objective Patients with bladder cancer (BCa) have a poor prognosis and are prone to metastasis. Deficiency of 1,25-dihydroxyvitamin D3 (VD) is associated with increased incidence and decreased survival in various tumors.
Jian Zhou   +5 more
doaj   +2 more sources

Fructose in the kidney: from physiology to pathology [PDF]

open access: yesKidney Research and Clinical Practice, 2021
The Warburg effect is a unique property of cancer cells, in which glycolysis is activated instead of mitochondrial respiration despite oxygen availability.
Takahiko Nakagawa, Duk-Hee Kang
doaj   +1 more source

Warburg effect‐related risk scoring model to assess clinical significance and immunity characteristics of glioblastoma

open access: yesCancer Medicine, 2023
Background Glioblastoma (GBM), the most common primary malignant brain tumor, has a poor prognosis, with a median survival of only 14.6 months.
Rong Zhang   +9 more
doaj   +1 more source

Research Progress on Regulatory Mechanism of Ubiquitin Modification on Warburg Effect in Malignant Tumors

open access: yesZhongliu Fangzhi Yanjiu, 2022
Ubiquitin modification and Warburg effect play an important role in the occurrence and development of tumors. The process of tumor ubiquitin modification is closely related to glycolysis, that is, ubiquitin modification in tumor cells can regulate the ...
WANG Fengli, HU Jing
doaj   +1 more source

Warburg effect in colorectal cancer: the emerging roles in tumor microenvironment and therapeutic implications

open access: yesJournal of Hematology & Oncology, 2022
Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer-related death worldwide. Countless CRC patients undergo disease progression.
Xinyang Zhong   +7 more
doaj   +1 more source

Hydrogen Sulfide Ameliorates Angiotensin II-Induced Atrial Fibrosis Progression to Atrial Fibrillation Through Inhibition of the Warburg Effect and Endoplasmic Reticulum Stress

open access: yesFrontiers in Pharmacology, 2021
Atrial fibrosis is the basis for the occurrence and development of atrial fibrillation (AF) and is closely related to the Warburg effect, endoplasmic reticulum stress (ERS) and mitochondrion dysfunctions-induced cardiomyocyte apoptosis. Hydrogen sulfide (
Heng-Jing Hu   +12 more
doaj   +1 more source

PDGF Promotes the Warburg Effect in Pulmonary Arterial Smooth Muscle Cells via Activation of the PI3K/AKT/mTOR/HIF-1α Signaling Pathway

open access: yesCellular Physiology and Biochemistry, 2017
Background/Aims: The enhanced proliferation of pulmonary arterial smooth muscle cells (PASMCs) is a central pathological component in pulmonary arterial hypertension (PAH).
Yunbin Xiao   +9 more
doaj   +1 more source

The SIRT6-Autophagy-Warburg Effect Axis in Papillary Thyroid Cancer

open access: yesFrontiers in Oncology, 2020
As shown in our previous study, SIRT6 promotes an aggressive phenotype and the epithelial-mesenchymal transition (EMT) in papillary thyroid cancer (PTC). In this study, we focused on the regulatory axis including SIRT6, autophagy, and the Warburg effect.
Zhou Yang   +5 more
doaj   +1 more source

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