Results 181 to 190 of about 157,233 (338)

Bimetallic Nanozyme Amplifier for Synergistic Ferroptosis‐Cuproptosis and Metabolic Reprogramming to Reshape Immunosuppressive Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
The Bimetallic Nanozyme Amplifier (PEG@AuCZ@CC) to maximize hydrogen peroxide production and reprogram tumor metabolism from glycolysis to oxidative phosphorylation. This shift enhances ferroptotic/cuproptotic signaling cascades and creates a glucose‐enriched but lactate‐depleted tumor microenvironment (TME), effectively overcoming immune tolerance in ...
Jianzhang Luo   +9 more
wiley   +1 more source

A Dual‐Target Recognition System Based on Acid‐Degradable Ni‐MOF and Aptamer Guidance for Precise Tumor Diagnosis and Combined Therapy

open access: yesAdvanced Science, EarlyView.
This work reports a Ni‐doped ZIF‐8 nanoplatform co‐encapsulating glucose oxidase and horseradish peroxidase, enabling a cascade catalytic reaction that produces hydroxyl radicals from endogenous glucose and hydrogen peroxide. Upon near‐infrared irradiation, the system simultaneously achieves photothermal and chemodynamic therapy, offering an effective ...
Jing Xu   +8 more
wiley   +1 more source

Brain and Eye Malformations Resembling Walker–Warburg Syndrome Are Recapitulated in Mice by Dystroglycan Deletion in the Epiblast [PDF]

open access: hybrid, 2008
Jakob S. Satz   +6 more
openalex   +1 more source

Synergistic Ni‐Co Metal Nodes in a Conjugated MOF‐Modified Separator for High‐Performance Lithium‐Sulfur Batteries

open access: yesAdvanced Science, EarlyView.
In this work, the employment of cMOFs is reported as modified materials for LSB separators. It is proved that cMOF with in‐plane d‐π conjugation is a good barrier layer for constructing high‐performance LSBs. Through a series of in situ and non in situ electrochemical examinations, LSB assembled with Ni1.35Co1.65(HHTP)2 separator exhibits excellent ...
Yuanhang Xu   +6 more
wiley   +1 more source

Ethnically diverse causes of Walker-Warburg syndrome (WWS):FCMDmutations are a more common cause of WWS outside of the Middle East [PDF]

open access: gold, 2008
M. Chiara Manzini   +16 more
openalex   +1 more source

New York and the politics of central banks, 1781 to the Federal Reserve Act [PDF]

open access: yes
The paper provides a brief history of central banking institutions in the United States. Specifically, the authors highlight the role of New York banking interests in the legislations affecting the creation or expiration of central banking institutions ...
Ellis W. Tallman, Jon R. Moen
core  

Bioenergetics of cancer cells: insights into the Warburg effect and regulation of ATP synthase. [PDF]

open access: yesMol Med
Del Dotto V   +6 more
europepmc   +1 more source

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