Results 41 to 50 of about 167,167 (358)
Nonlinear Multi-Objective Flux Balance Analysis of the Warburg Effect [PDF]
arXiv, 2021 Due to its implication in cancer treatment, the Warburg Effect has received extensive in silico investigation. Flux Balance Analysis (FBA), based on constrained optimization, was successfully applied in the Warburg Effect modelling. Yet, the assumption that cell types have one invariant cellular objective severely limits the applicability of the ...
arxiv
4 open, 2019 It is increasingly evident that carcinogenesis, in the vast majority of cancers, cannot be explained simply through an accumulation of somatic mutations, or epigenetics, the stem cell theory, or the Warburg effect.
Brücher Björn L.D.M., Jamall Ijaz S.
doaj +1 more source
Theranostics, 2021 Metabolic reprogramming, especially Warburg effect, is a key event in tumor initiation and progression. ZEB1 plays a vital role in metastasis of various cancers.
Yanming Zhou +15 more
semanticscholar +1 more source
Microenvironmental cooperation promotes early spread and bistability of a Warburg-like phenotype [PDF]
Scientific Reports 7, 3103 (2017), 2017 We introduce an in silico model for the initial spread of an aberrant phenotype with Warburg-like overflow metabolism within a healthy homeostatic tissue in contact with a nutrient reservoir (the blood), aimed at characterizing the role of the microenvironment for aberrant growth.
arxiv +1 more source
Fractality in tumor growth at the avascular stage from a generalization of the logistic-Gompertz dynamics [PDF]
, 2022 The dynamics between healthy and malignant cells at the avascular stage of growth is described by a set of chemical reactions representing the populations of both types of cells. We obtain a generalization of the logistic-Gompertz dynamics and study the consequences in terms of the properties of tumor growth associated with the Warburg effect, mitosis ...
arxiv +1 more source
Reflections on teaching art history in art schools paper given, 4th January, 1966 [PDF]
Journal of Art Historiography, 2022 With the creation of the Dip. A. D., formal teaching of art history became mandated in the Uk’s art schools. In a talk to university heads of art history, who would be required to train the required art historians, Gombrich addressed the problem of what ...
E. H. Gombrich
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Oxidative Medicine and Cellular Longevity, 2022 Identification of innovative therapeutic targets for the treatment of cognitive impairment in Parkinson’s disease (PD) is urgently needed. Hydrogen sulfide (H2S) plays an important role in cognitive function.
Qing Tian +6 more
semanticscholar +1 more source
Data of oxygen- and pH-dependent oxidation of resveratrol
Data in Brief, 2016 We show here if under physiologically relevant conditions resveratrol (RSV) remains stable or not. We further show under which circumstances various oxidation products of RSV such as ROS can be produced.
Annabell Plauth +12 more
doaj +1 more source
Cell Death and Disease, 2020 N6-methyladenosine (m6A) serves as the most common and conserved internal transcriptional modification. However, the roles of m6A on cervical cancer (CC) tumorigenesis are still unclear.
Qian-qing Wang +6 more
semanticscholar +1 more source
The Warburg effect and its role in cancer detection and therapy [PDF]
, 2009 The Warburg effect is a cellular phenomenon in cancer cells discovered by Otto Warburg in 1924. His findings showed that in normoxic conditions tumor cells primarily use glycolysis for energy production instead of mitochondrial oxidative phosphorylation ...
Christ, Ethan J.
core +2 more sources