Results 131 to 140 of about 108,453 (351)

Review of: "Targeting the Warburg Effect with Glucosodiene: A Case Report of a 43-year-old Female after Mastectomy of the right breast and axillary clearance with Successful First Case Treatment for Metastatic Triple Negative Breast Cancer (TNBC) of Bone" [PDF]

, 2023
Saranyadevi Saranyadevi
openalex   +1 more source

NFS1 Regulates IDH2 to Attenuate Abdominal Aortic Aneurysms via Interacting With SP2

Advanced Science, EarlyView.
The loss of NFS1 leads to its reduced binding with the transcription factor SP2, resulting in decreased expression of the downstream gene Idh2. This causes a shift in energy supply toward glycolysis in VSMCs, ultimately contributing to the occurrence and progression of AAA.
Luzheng Zhang, Yu Zhang, Dezhong Wen, Suxiang Guo, Xiaohui Qi, Heng Wang, Yujin Sun, Guangdong Yang, Yuehong Wang, Song Xue   +9 more
wiley   +1 more source

ASPP2 suppresses tumour growth and stemness characteristics in HCC by inhibiting Warburg effect via WNT/β‐catenin/HK2 axis [PDF]

, 2023
Beibei Liang, Yuan Jiang, Shaohua Song, Wei Jing, Hao Yang, Li Zhao, Ya Chen, Qiqi Tang, Xuhui Li, Lisha Zhang, Haili Bao, Gang Huang, Jian Zhao   +12 more
openalex   +1 more source

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

Predictive significance of glycolysis-associated lncRNA profiles in colorectal cancer progression

BMC Medical Genomics
Background The Warburg effect is a hallmark characteristic of colorectal cancer (CRC). Despite extensive research, the role of long non-coding RNAs (lncRNAs) in influencing the Warburg effect remains incompletely understood.
Rui Mao, Chenxin Xu, Quanzheng Zhang, Zheng Wang, Yanjun Liu, Yurui Peng, Ming Li   +6 more
doaj   +1 more source

Supplementary Data from Endogenous Retroelement Activation by Epigenetic Therapy Reverses the Warburg Effect and Elicits Mitochondrial-Mediated Cancer Cell Death

, 2023
Vicente Fresquet, María J. García‐Barchino, Marta Larráyoz, Jon Celay, Carmen Vicente, Marta Fernández‐Galilea, Maria J. Larrayoz, Marı́a José Calasanz, Carlos Panizo, Alexandra Junza, Jiahuai Han, Celia Prior, Puri Fortes, Rubén Pı́o, Julen Oyarzábal, Alvaro Martínez-Baztan, Bruno Paiva, María J. Moreno‐Aliaga, María D. Odero, Xabier Agirre, Óscar Yanes, Felipe Prósper, José A. Martínez-Climent   +22 more
openalex   +1 more source

NEIM-11 DEUTERIUM METABOLIC IMAGING (DMI) DETECTS A LARGER WARBURG EFFECT IN HIGH-GRADE BRAIN TUMORS AND IN IDH WILD TYPE GLIOMAS [PDF]

, 2023
Lauren Kim, Henk De Feyter, Robin de Graaf, Robert K. Fulbright, Yanning Liu, Douglas L. Rothman, Joachim M. Baehring, Nicholas Blondin, Peter Kim, Omuro Antonio, Veronica Chiang, Jennifer Moliterno, Sacit Bulent Omay, Joseph M. Piepmeier, Zachary Corbin   +14 more
openalex   +1 more source

Beyond Catalytic Therapy: Copper‐Paeonol Nanozymes Disrupt Fascin‐Mediated Actin Bundling to Suppress Tumor Growth and Metastasis

Advanced Science, EarlyView.
Copper‐paeonol nanozymes target tumor‐specific reactive oxygen species generation and disrupt fascin‐mediated actin bundling, effectively suppressing tumor growth and metastatic colonization. Abstract Fascin, an actin‐bundling protein universally upregulated in metastatic tumors, drives tumor migration and invasion by promoting filopodia and ...
Peiying Zhang, Huajun Li, Yisen Wang, Jie Xiang, Lei Fan, Shengzhe Zhang, Lizeng Gao, Hua Dai, Juqun Xi   +8 more
wiley   +1 more source

A New Target for Hepatic Fibrosis Prevention and Treatment: The Warburg Effect

Frontiers in Bioscience-Landmark
Hepatic fibrosis is a major public health problem that endangers human wellbeing. In recent years, a number of studies have revealed the important impact of metabolic reprogramming on the occurrence and development of hepatic fibrosis.
Meng Pan, Huanyu Li, Xiaoyan Shi
doaj   +1 more source

5′tRF‐GlyGCC Promotes Breast Cancer Progression via LDHA‐Mediated Glycolysis and Macrophage Polarization

Advanced Science, EarlyView.
5’tRF‐GlyGCC promotes breast cancer malignancy by binding to LDHA. This interaction, facilitated by FGFR1 and LDHA phosphorylation, enhances glycolysis. Additionally, 5’tRF‐GlyGCC/LDHA signaling recruits and polarizes macrophages into a pro‐tumor M2 state via CCL7, thus remodeling the tumor microenvironment.
Cheng Yi, Yunqing Lu, Xing Chang, Ying Wang, Jiawang Zhou, Guoyou Xie, Lijun Tao, Zhaotong Wang, Yifan Tian, Lihong Wang, Feng Tang, Yijing Zheng, Xinchen Yue, Jinping Lei, Xiansong Wang, Lichen Ge, Zhuojia Chen, Hongsheng Wang   +17 more
wiley   +1 more source