Results 131 to 140 of about 145,467 (273)

UK Biobank: Transforming drug discovery and precision medicine

British Journal of Pharmacology, EarlyView.
UK Biobank is a large‐scale, prospective study with extensive genetic and phenotypic data on half a million individuals. Volunteers, aged between 40 and 69 years, were recruited between 2006 and 2010 from the general population of the United Kingdom.
Jelena Bešević, Saredo Said, Reka Nagy, Yalda Jamshidi, Christopher D. Whelan, Lauren Carson, Martin K. Rutter, Adam J. Lewandowski, Mark Effingham, Rory Collins, Ben Lacey, Naomi E. Allen   +11 more
wiley   +1 more source

Ascorbic acid-induced warfarin resistance after breast cancer surgery: a case report and literature review

Frontiers in Pharmacology
Warfarin is an anticoagulant that requires INR-based dosage adjustment. Ascorbic acid may impair warfarin effectiveness according to limited literature.
Pingfa Gao, Yang Shen, Ping Wu, Wenjie Lv, Wenjie Lv   +4 more
doaj   +1 more source

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

GROWTH AND SURVIVAL OF RATS FED SWINE DIETS SUPPLEMENTED WITH VITAMIN K AND/OR WARFARIN [PDF]

, 1986
Robert W. Jones, R. A. Easter
openalex   +1 more source

Association between CMR‐derived hepatic T1‐time, tricuspid regurgitation and survival

European Journal of Clinical Investigation, EarlyView.
We investigated the association between tricuspid regurgitation (TR) severity and hepatic T1‐time in 1029 patients undergoing cardiac MRI and echocardiography. Hepatic T1‐time increased progressively with TR severity and remained independently associated after adjusting for NT‐proBNP and right ventricular function. Both TR and hepatic T1‐time predicted
Katharina Mascherbauer, Christina Kronberger, Manuel Gruber, Carolina Donà, Matthias Koschutnik, Varius Dannenberg, Michael Poledniczek, Laura Lunzer, Christian Nitsche, Franz Duca, Gregor Heitzinger, Kseniya Halavina, Dietrich Beitzke, Christian Loewe, Michael Trauner, Philipp Bartko, Julia Mascherbauer, Christian Hengstenberg, Andreas Kammerlander, Elisabeth Waldmann   +19 more
wiley   +1 more source

Efficacy of three anticoagulant rodenticides for the control of poison-shy Rattus rattus [PDF]

, 1984
House rats (Rattus rattus) which do not consume a lethal dose of zinc phosphide develop poison-shyness after a single exposure. The surviving poison-shy rats cannot be baited again with zinc phosphide for about three months.
Bhardwaj, Devendra, Prakash, Ishwar
core  

Vitamin K lowered the international normalised ratio into the therapeutic range in patients receiving warfarin [PDF]

, 2001
Brian P. Schmitt
openalex   +1 more source

Effectiveness of direct oral anticoagulants for all‐cause mortality and cardiovascular events in overweight and obese patients with atrial fibrillation: Insight from the nationwide START registry

European Journal of Clinical Investigation, EarlyView.
This study shows that overweight and obese patients with atrial fibrillation experience improved outcomes when treated with DOACs compared with VKAs. Specifically, DOAC use was associated with lower risks of all‐cause mortality and cardiovascular events.
Danilo Menichelli, Gianluca Gazzaniga, Emilia Antonucci, Gualtiero Palareti, Daniela Poli, Pasquale Pignatelli, Daniele Pastori, the START2 Register Investigators, Benilde Cosmi, Daniela Poli, Elena Lotti, Martina Berteotti, Walter Ageno, Giovanna Colombo, Salvatore Bradamante, Eugenio Bucherini, Monica Vastola, Paola Casasco, Antonio Chistolini, Alessandra Serrao, Luciano Crippa Ambulatorio Emostasi, Raimondo De Cristofaro, Erica De Candia, Valeria De Micheli, Marcello Di Nisio, Anna Falanga, Teresa Lerede, Elvira Grandone, Donatella Colaizzo, Antonio Insana, Nicola Lucio Liberato, Domenico Lione, Rosa Maria Lombardi, Giacomo Lucarelli, Giuseppe Malcangi, Catello Mangione, Giuliana Martini Centro Emostasi, Marco Marzolo, Giovanni Nante, Vincenzo Oriana, Paolo Pedico, Simona Pedrini, Vittorio Pengo, Antonietta Piana, Francesco Cibecchini, Simona Pezzella, Pasquale Pignatelli, Daniele Pastori, Vincenza Rossi, Lucia Ruocco, Paolo Chiarugi, Serena Rupoli, Domizio Serra, Carmine Spataro, Margherita Reduzzi, Sophie Testa, Oriana Paoletti, Vincenzo Toschi, Claudio Vasselli   +58 more
wiley   +1 more source

Exploring Fall‐Related Fracture Risk by Possible Fall‐Risk Increasing Drugs in Japanese Older Adults Using Municipal Linked Medical and Long‐Term Care Claim Data: A Nested Case‐Control and Case‐Crossover Study

Geriatrics &Gerontology International, EarlyView.
ABSTRACT Aim We examined the association between the use of fall‐risk‐increasing drugs (FRIDs) and other medications, and the risk of fall‐related fractures in Japanese community‐dwelling older adults. Methods We used linked medical and long‐term care insurance claims data from Tsukuba City, Japan (2014–2019).
Hiroya Nakano, Masao Iwagami, Jun Komiyama, Yu Sun, Yoko Hamasaki, Yuta Taniguchi, Naoaki Kuroda, Ai Suzuki, Nanako Tamiya   +8 more
wiley   +1 more source

Measuring Direct Oral Anticoagulant (DOAC) Levels: Applications, Limitations, and Future Directions

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction There are important challenges with the measurement and interpretation of direct oral anticoagulant (DOAC) anticoagulant effect including a lack of therapeutic ranges, inaccuracy of routinely available coagulation assays, lack of established thresholds for clinically significant effect, and uncertainty about how to apply the ...
Siraj Mithoowani, Chee Wee Tan, Deborah M. Siegal   +2 more
wiley   +1 more source