Results 131 to 140 of about 192,309 (409)

Knowledge of warfarin therapy among patients attending Warfarin Clinic at a Public Hospital in Northern part of Malaysian Peninsular

Archives of Pharmacy Practice, 2016
Background: Patient′s knowledge of anticoagulation therapy is important to achieving and maintaining optimal therapy outcome as well as reducing adverse events.
Teoh Boon Ching, Syed Azhar Syed Sulaiman, Amal K Suleiman, Syed Wasif Gillani, Usman Abubakar   +4 more
doaj   +1 more source

Safety and effectiveness of apixaban compared to warfarin in dialysis patients

Research and Practice in Thrombosis and Haemostasis, 2018
Essentials The safety of apixaban in patients on dialysis is currently debated. Bleeding events were retrospectively compared for dialysis patients on warfarin vs apixaban.
D. Reed, Surabhi Palkimas, R. Hockman, Sumner Abraham, T. Le, Hillary S Maitland   +5 more
semanticscholar   +1 more source

Impact of Age and Factor Xa Inhibitor Concentrations on Bleeding Risk in Patients with Atrial Fibrillation

Clinical Pharmacology &Therapeutics, EarlyView.
This study aimed to analyze differences in the exposure‐response relationship for factor Xa inhibitors (FXaI) between patients aged ≥ 80 and < 80 years. Patients with atrial fibrillation (AF) taking rivaroxaban, apixaban, or edoxaban were enrolled, and a single steady‐state trough concentration was measured.
Shin‐Yi Lin, Yen‐Bing Liu, Li‐Ting Ho, Ching‐Hua Kuo, Yu‐Fong Peng, Chih‐Fen Huang, Sung‐Chun Tang, Jiann‐Shing Jeng   +7 more
wiley   +1 more source

The application of a perceptron model to classify an individual's response to a proposed loading dose regimen of Warfarin [PDF]

arXiv, 2012
The dose regimen of Warfarin is separated into two phases. Firstly a loading dose is given, which is designed to bring the International Normalisation Ratio (INR) to within therapeutic range. Then a stable maintenance dose is given to maintain the INR within therapeutic range.
arxiv  

Association Between Dabigatran vs Warfarin and Risk of Osteoporotic Fractures Among Patients With Nonvalvular Atrial Fibrillation

Journal of the American Medical Association (JAMA), 2017
Importance The risk of osteoporotic fracture with dabigatran use in patients with nonvalvular atrial fibrillation (NVAF) is unknown. Objective To investigate the risk of osteoporotic fracture with dabigatran vs warfarin in patients with NVAF.
W. Lau, E. Chan, C. Cheung, C. Sing, K. Man, G. Lip, C. Siu, J. Lam, Alan C H Lee, I. Wong   +9 more
semanticscholar   +1 more source

Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) [PDF]

, 2011
<p>Background: Venous thromboembolic events (VTE), including deep venous thrombosis and pulmonary embolism, are common in older age. It has been suggested that statins might reduce the risk of VTE however positive results from studies of middle ...
A Gaw, A Squizzato, A Squizzato, AD Blann, AG Holst, Allan Gaw, AM Wallace, Ann Rumley, Anton JM de Craen, AW Tsai, CC Yang, CJ Doggen, CJ Packard, D Grady, David J Stott, Dilys J Freeman, DJ Stott, E Ann Brown, Edward S Tobias, FR Rosendaal, FR Rosendaal, GD Lowe, Gordon DO Lowe, HT Sorensen, I Ford, Ian A Greer, Ian Ford, J Shepherd, J Shepherd, J Wouter Jukema, JG Ray, K Lacut, KA Darvall, KI Paraskevas, L Smeeth, M Cushman, Marijke Frölich, Michele Robertson, N Sattar, Naveed Sattar, P Eline Slagboom, P Poredos, RJ Glynn, RJ Glynn   +43 more
core   +4 more sources

ESR1 Variants and Subcontinental Genomic Ancestry: Insights from the 1000 Genomes Project and Native American Populations

Clinical Pharmacology &Therapeutics, EarlyView.
The ESR1 gene is relevant in breast cancer treatments in the pharmacogenetics context. However, Native, African, and mixed populations are known to be underrepresented in genomic studies. This is particularly important given that the difference in variants' frequencies among different populations can lead to population‐specific clinical implications ...
Mariana M. Scudeler, Caíque Manóchio, Bruno Miwa, Guilherme Belfort‐Almeida, Lucas Faria‐Costa, Cesar Sanchez, Carlos Padilla, Omar Caceres, Eduardo Tarazona‐Santos, Heinner Guio, Timothy D. O'Connor, Fernanda Rodrigues‐Soares   +11 more
wiley   +1 more source

Extended use of dabigatran, warfarin, or placebo in venous thromboembolism.

New England Journal of Medicine, 2013
BACKGROUND Dabigatran, which is administered in a fixed dose and does not require laboratory monitoring, may be suitable for extended treatment of venous thromboembolism.
S. Schulman, C. Kearon, A. Kakkar, S. Schellong, H. Eriksson, David Baanstra, A. M. Kvamme, J. Friedman, P. Mismetti, S. Goldhaber   +9 more
semanticscholar   +1 more source

Thrombolysis in a stroke patient on dabigatran anticoagulation: case report and synopsis of published cases [PDF]

, 2013
We present the case of an aphasic 77-year-old stroke patient with left distal M1 occlusion who received rt-PA for thrombolysis while on oral anticoagulant treatment with dabigatran (150 mg b.i.d.).
Abruscato, Mario Giovanni Rosario, Baas, Horst, Hövelmann, Susanne, Pfeilschifter, Waltraud   +3 more
core   +2 more sources

UHPLC‐QTOFMS Urine Drug Screening With Dilute‐and‐Shoot Sample Preparation and Vacuum‐Insulated Probe‐Heated Electrospray Ionization

Drug Testing and Analysis, EarlyView.
The new ionization technique, vacuum‐insulated probe‐heated electrospray, allows for a simple dilute‐and‐shoot sample preparation to be used with liquid chromatography time‐of‐flight mass spectrometry in urine drug screening. Comparison with a method relying on solid‐phase extraction and conventional electrospray ionization shows improved performance ...
Mira Sundström, Pirkko Kriikku, Ilkka Ojanperä, Carsten Baessmann, Anna Pelander   +4 more
wiley   +1 more source