Results 241 to 250 of about 102,210 (307)

Direct oral anticoagulants versus vitamin K antagonists after left atrial appendage occlusion: a systematic review and meta-analysis. [PDF]

BMC Cardiovasc Disord
Dai Y, Chang J, Guo J.
europepmc   +1 more source

"Left Atrial Appendage Closure Versus Medical Therapy in Atrial Fibrillation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials". [PDF]

J Cardiovasc Electrophysiol
Al-Janabi AAH, Al-Shammari AS, Hageen AW, Al-Tuaama AZH, Al-Ibraheem AMT, Shahzaib M, Rathi D, Hamzah KA, Shweliya MA, Kurmasha YH, Wagdy M, Refaat MM.   +11 more
europepmc   +1 more source

A Practical Alternative to Refine the Estimate of fmCYP3A4 and Evaluate Drug–Drug Interaction Potential for Ziftomenib Using PBPK Modeling to Inform Labeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 9, September 2026.
ABSTRACT Accurate physiologically based pharmacokinetic (PBPK) simulation of drug–drug interaction (DDI) potential requires estimation of the relative contribution of the impacted pathway. While fraction metabolized by CYP enzymes is usually estimated using dedicated clinical DDI studies with strong CYP inhibitors, this approach might not be available ...
Ian E. Templeton, Chara Litou, Hannah M. Jones, Julie Mackey Ahsan, Marilyn Tabachri, Mollie Leoni, Amitava Mitra   +6 more
wiley   +1 more source

Comparative efficacy and safety of direct oral anticoagulants versus warfarin in non-valvular atrial fibrillation patients with adult congenital heart disease. Contemporary real-world propensity-matched retrospective cohort study. [PDF]

Int J Cardiol Congenit Heart Dis
Kumi DD, Blankson G, Acheampong IA, Odoi SM, Mungee S, Baman T, Mehrotra A, Shah S.   +7 more
europepmc   +1 more source

Adjoint and Unrolled Automatic Differentiation for Laplace‐Approximated Likelihoods in Population PK and PK/PD Models

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 9, September 2026.
ABSTRACT Maximum likelihood estimation in population pharmacokinetic/pharmacodynamic (PK/PD) nonlinear mixed‐effects (NLME) models targets fixed‐effect, interindividual‐variability, and residual‐variability parameters through a marginal likelihood that integrates each subject's contribution over individual random effects.
Guido H. Jajamovich, William Holmes, Chih‐Wei Lin, Khamir Mehta   +3 more
wiley   +1 more source

Self-Administered Dietary Supplements, Herbal Products, and Ergogenic Aids Before Plastic Surgery: A Narrative Review and the PLASTIC-S Perioperative Management Framework. [PDF]

Cureus
Sousa Oliveira LA, Cabette Filho NN, Sacksida Valladão VDC, Mendes LH, Zanella FA.   +4 more
europepmc   +1 more source

Emerging Chemical Upcycling and Repurposing Strategies for Waste Pharmaceuticals

ChemistrySelect, Volume 11, Issue 36, 22 September 2026.
What could be done with pharmaceutical waste from a circular chemistry perspective? A literature survey was conducted using the terms “recycling”, “upcycling”, “reuse”, “repurposing”, “pharmaceutical”, “expired drug”, “expired medicine”, “unused drug” and “unused medicine” in the databases Scopus, Web of Science and Periódicos CAPES to answer this ...
Letícia Ribeiro Magalhães, Lourena Mafra Veríssimo, Euzébio Guimarães Barbosa, Alessandro Kappel Jordão   +3 more
wiley   +1 more source

OFDI-Guided Stentless PCI for Erosion-Related STEMI Unmasking Antiphospholipid Syndrome. [PDF]

JACC Case Rep
Saito A, Enomoto Y, Terashima R, Miyake W, Yamamoto M, Hara H, Hiroi Y.   +6 more
europepmc   +1 more source

Analysis of the clinical characteristics of warfarin-associated purple toe syndrome. [PDF]

Clin Exp Med
Shi C, Zhang S, Chen S, Guo R, Wu T.
europepmc   +1 more source

Atrial Fibrillation in Cardiac Amyloidosis: A Multicenter Experience Comparing Novel Oral Anticoagulants and Warfarin. [PDF]

J Cardiovasc Dev Dis
Abdul Nabi H, Dreher L, Liu M, Al Osta S, Karikalan SA, Habib E, El Masry HZ.   +6 more
europepmc   +1 more source