Results 51 to 60 of about 74,860 (159)

Correlation between single nucleotide polymorphisms in CYP4F2 and warfarin dosing in chinese valve replacement patients

Journal of Cardiothoracic Surgery, 2012
Background Individuals with implanted mechanical valve prostheses require lifelong anticoagulation therapy with warfarin. The narrow therapeutic index of warfarin makes it difficult to dose and maintain proper anticoagulation.
Li Jie-Hui, Ma Guo-Guo, Zhu Shu-Qiang, Yan Hao, Wu Yong-Bing, Xu Jian-Jun   +5 more
doaj   +1 more source

Association between Cytochrome P450 2 C9 and Vitamin K Epoxide Reductase Complex Subunit 1 Polymorphisms with Warfarin dose among Iranian Patients

Research in Molecular Medicine, 2016
Background: Warfarin is a common anticoagulant drug that has a narrow therapeutic index; higher dose causes excessive bleeding and lower dose leads to cerebrovascular clotting and stroke in patients.
Reyhaneh Kameli, Mandana Hasanzad, Zahra Tahmasebi Fard, Mojgan Babanejad, Mahdieh Imeni, Lotfollah Feizi Barnaji, Atoosa Madadkar, Seyed Hamid Jamaldini   +7 more
doaj  

Knowledge of warfarin therapy among patients attending Warfarin Clinic at a Public Hospital in Northern part of Malaysian Peninsular

Archives of Pharmacy Practice, 2016
Background: Patient′s knowledge of anticoagulation therapy is important to achieving and maintaining optimal therapy outcome as well as reducing adverse events.
Teoh Boon Ching, Syed Azhar Syed Sulaiman, Amal K Suleiman, Syed Wasif Gillani, Usman Abubakar   +4 more
doaj   +1 more source

Comparison of Temporary Interruption of Warfarin Therapy for 3 and 5 days before Surgery in Thailand: A Randomized Controlled Trial

Siriraj Medical Journal, 2017
Objective: The ACCP guideline 2008 recommended cessation of warfarin five days before surgery. However, based on the observation of the clinical practice at Siriraj Hospital, we suggested a shorter period of three days before surgery.
Angsu Chartrungsan, Pansak Laksanabunsong, Akarin Nimmannit, Bundarika Bundarika Suwanawiboon, Naravat Poungvarin, Wanchai Wongkornrat, Kriangkrai Tantiwongkosri, Worawong Slisatkorn, Pranya Sakiyalak, Punnarerk Thongcharoen, Thaworn Subtaweesin, Somchai Sriyoschati, Teeravit Phanchaipetch   +12 more
doaj  

Number needed to treat for net clinical benefit of oral anticoagulants in Asian patients with atrial fibrillation

Journal of Arrhythmia
Background Oral anticoagulants (OAC) can reduce ischemic stroke/systemic embolism (SSE) in patients with non‐valvular atrial fibrillation (AF) while increasing the risk of major bleeding. We aimed to analyze the number needed to treat for the net benefit
Rungroj Krittayaphong, Satchana Pumprueg, Ahthit Yindeengam, Gregory Y. H. Lip   +3 more
doaj   +1 more source

Correlation between Metabolic Parameters and Warfarin Dose in Patients with Heart Valve Replacement of Different Genotypes

Reviews in Cardiovascular Medicine
Background: Warfarin has become the first choice for anticoagulation in patients who need lifelong anticoagulation due to its clinical efficacy and low price.
Xiaowu Wang, Diancai Zhao, Jipeng Ma, Xia Wang, Jincheng Liu   +4 more
doaj   +1 more source

Mechanism of exacerbation of traumatic brain injury under warfarin anticoagulation in male mice.

PLoS ONE
IntroductionTraumatic brain injury (TBI) is exacerbated in patients on antithrombotic medications, with warfarin leading to increased bleeding in some cases.
Yuki Tatara, Ken-Ichiro Nakao, Ryo Shimada, Kazuhiko Kibayashi   +3 more
doaj   +1 more source

Warfarin paradox [PDF]

British Dental Journal, 2013
openaire   +2 more sources

Alternative therapy interaction with warfarin: what doctors should know

Кардиоваскулярная терапия и профилактика, 2010
Warfarin effectiveness and safety is substantially affected by concurrent therapy. This paper reviews the main mechanisms of warfarin interactions with other agents, which underlie adverse effect development: platelet dysfunction, gastro-intestinal ...
T. B. Kozlova, T. V. Taratuta, M. B. Aksenova, T. V. Khlevchuk   +3 more
doaj  

Analysis of potential interactions between warfarin and prescriptions in Estonian outpatients aged 50 years or more

Pharmacy Practice, 2012
In Estonia, warfarin is widely prescribed by general practitioners to prevent and treat thromboembolic diseases. To date, there has been no systematic analysis of the potential risk of warfarin interactions with other drugs in the outpatient population ...
Gavronski M, Hartikainen S, Zharkovsky A, Sautenkova N   +3 more
doaj