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BMC Genetics, 2010 Background Certain mutations in the vitamin K epoxide reductase subcomponent 1 gene (vkorc1) mediate rodent resistance to warfarin and other anticoagulants. Testing for resistance often involves analysis of the vkorc1.
Borchert Jeff N +4 more
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CLINICAL PHARMACOLOGY OF FLOROCHINOLONS: A FOCUS ON SAFETY. Review
Медична наука України, 2019 Fluoroquinolones are effective in the treatment of infections of almost any localization (upper and lower respiratory tract, urinary system, skin and soft tissues, bones and joints, liver and bile ducts, gastrointestinal tract, female genital tract ...
M.V. Khaitovych
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DNA-based field monitoring of warfarin resistance in rats (Rattus norvegicus)
, 2007 Missense mutations in a hitherto unknown gene VKORC1, have recently been shown to confer resistance to anticoagulant rodenticides in rodents. This discovery provided new opportunities for improving resistance-testing methodology by molecular-biological
Müller, Clemens R. +2 more
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Julius-Kühn-Archiv, 2011 Anticoagulant resistance was first discovered in UK Norway rats (Rattus norvegicus Berk.) in 1958 and has been present ever since. The possible detrimental impact of resistance on effective rodent control was quickly recognised and, for almost three ...
Buckle, A.
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Clinical Cardiology, Volume 49, Issue 10, October 2026.Genomic medicine in cardiovascular care is progressing from established diagnostic applications toward integrated risk prediction, multiomics, and emerging therapeutic strategies. ABSTRACT Background Genomic cardiology is an emerging field integrating genetic, molecular, imaging, and digital health data to improve cardiovascular disease (CVD ...
Neda Mohsen‐Pour +5 more
wiley +1 more source
Warfarin metabolism and disposition in anticoagulant-resistant and susceptible mouse strains. [PDF]
, 2018 The differential susceptibilities of warfarin-susceptible LAC-grey and warfarin-resistant HC house mice to the anticoagulant effect of the oral rodenticide 3-(alpha-acetonyl benzyl)-4-hydroxycoumarin (Warfarin) in terms of their blood clotting times ...
Sutcliffe, Frances Anne.
core
Julius-Kühn-Archiv, 2011 The Westphalian resistant Norway rat strain is characterised by the possession of the Y139C variant of the vkorc1 gene, and practical resistance occurs in rat infestations at different frequencies to the anticoagulants warfarin, coumatetralyl ...
Klemann, N., Esther, A., Endepols, S.
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From Exposure to Guided Participation: Designing Experiential Education as Cognitive Apprenticeships
JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 10, October 2026.ABSTRACT Experiential pharmacy education is expected to develop trainees who can participate in patient care, reason through ambiguity, communicate with interprofessional teams, and progress toward practice‐ready or independent performance. Pharmacy practice experiences are often organized around clinical exposure, topic discussions, patient ...
W. Anthony Hawkins +2 more
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The biochemistry of warfarin resistance in the rat [PDF]
Biochemical Journal, 1970 R J, Davis, B H, Davies
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Journal of Arrhythmia, Volume 42, Issue 5, October 2026.ABSTRACT The 2026 Asia Pacific Heart Rhythm Society (APHRS) Guidelines represent the first comprehensive APHRS guidelines dedicated to the management of atrial fibrillation (AF) and comprise four parts covering epidemiology, detection/screening and integrated care; stroke prevention; rate and rhythm control; and lifestyle risk factor and comorbidity ...
Tze‐Fan Chao +15 more
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