Results 101 to 110 of about 1,498,287 (280)
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Mineral licks as environmental reservoirs of chronic wasting disease prions
PLoS ONE, 2018 Chronic wasting disease (CWD) is a fatal neurodegenerative disease of deer, elk, moose, and reindeer (cervids) caused by misfolded prion proteins. The disease has been reported across North America and recently discovered in northern Europe. Transmission
Ian H Plummer +4 more
semanticscholar +1 more source
Transformations to achieve the Sustainable Development Goals Includes the SDG Index and Dashboards. Sustainable Development Report 2019 [PDF]
, 2019 The Sustainable Development Report 2019 presents an updated SDG Index and Dashboards with a refined assessment of countries’ distance to SDG targets. The report has been successfully audited for the first time by the European Commission Joint Research ...
Fuller, G. +4 more
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Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source
Animal Industry News, 2009, Vol. 10, no. 1 [PDF]
, 2009 Newsletter produced by Department of Agriculture and Land Stewardship about the animal industry in ...
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Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz +3 more
wiley +1 more source
Transboundary and Emerging Diseases, 2018 A number of prion diseases affect humans, including Creutzfeldt-Jakob disease; most of these are due to genetic mutations in the affected individual and occur sporadically, but some result from transmission of prion proteins from external sources. Of the
L. Waddell +5 more
semanticscholar +1 more source
The Economic Effects of Chronic Wasting Disease (CWD) in Wisconsin [PDF]
Wisconsin's 600,000 deer hunters will bear the brunt of the economic losses from chronic wasting disease (CWD) in the Wisconsin deer herd. Though studies have not been done to pinpoint these losses, under plausible assumptions, they could have amounted ...
Bishop, Richard C.
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Animal Industry News, April 2006, Vol. 7, no. 1 [PDF]
, 2006 Newsletter produced by Department of Agriculture and Land Stewardship about the animal industry in ...
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