Results 111 to 120 of about 304,857 (302)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Combined Application of Multiple Global Change Factors Negatively Influences Key Soil Processes across an Urban Gradient in Berlin, Germany

Soil Systems
Urbanization is a growing phenomenon affecting soils worldwide. Urban centers have been highlighted as hotspots for global change factors due to heightened anthropogenic activity.
Peter Meidl, Daniel R. Lammel, Vladan Nikolic, Marie Decker, Mohan Bi, Leo Hampl, Matthias C. Rillig   +6 more
doaj   +1 more source

Spectroscopic characterizations of the mixed Langmuir-Blodgett (LB) films of 2,2'-biquinoline molecules: evidence of dimer formation

, 2008
This communication reports the -A isotherms and spectroscopic characterizations of mixed Langmuir and Langmuir-Blodgett (LB) films of nonamphiphilic 2, -biquinoline (BQ) molecules, mixed with polymethyl methacrylate (PMMA) and stearic acid (SA). The pi-A
Acharya, Barnes, Baudin, Brinkhuis, D. Bhattacharjee, Dorfler, Dutta, Dutta, Dutta, Liang, Mori, Mori, Ray, S. Biswas, S. Deb, S.A. Hussain, Sadrazedh, Schneider   +17 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Warming impacts on carbon, nitrogen and phosphorus distribution in soil water-stable aggregates

Plant, Soil and Environment, 2018
A five-year (2010-2015) field experiment was conducted to investigate warming impacts on organic carbon (OC), total nitrogen (TN) and total phosphorus (TP) contents and their ratios in bulk soil and soil water-stable aggregates in an alpine meadow of the
Song GUAN, Na AN, Jinhua LIU, Ning ZONG, Yongtao HE, Peili SHI, Jinjing ZHANG, Nianpeng HE   +7 more
doaj   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Nanoemulsion stability: experimental evaluation of the flocculation rate from turbidity measurements

, 2012
The coalescence of liquid drops induces a higher level of complexity compared to the classical studies about the aggregation of solid spheres. Yet, it is commonly believed that most findings on solid dispersions are directly applicable to liquid mixtures.
Adamson, Aguiar, Allain, Antonio M. Puertas, Aveyard, Aveyard, Aveyard, Ball, Barchini, Basheva, Beattie, Behrens, Behrens, Benoit, Bibette, Binks, Borwankar, Burnett, Chandrasekar, Clara Rojas, Cohen, Couder, Danov, Danov, Delmas, Derjaguin, Dhont, Dickinson, Dukhin, Eastoe, Ekwall, Elimelech, Evans, Feder, Finsy, Forgiarini, Friedlander, Fuchs, Gauer, Gauer, German Urbina-Villalba, Ghosh, Gregory, Grimes, Gutiérrez, Holt, Holt, Holthoff, Holthoff, Hu, Hunter, Ivanov, Izquierdo, Izquierdo, Kabalnov, Kabalnov, Kabalnov, Kabalnov, Kamogawa, Karaman, Kareem Rahn-Chique, Kerker, Koppel, Kramer, Lattuada, Lee, Lichtenbelt, Lifshitz, Lin, Lin, Lips, Lips, Liu, Lyklema, Maeda, Maestro, Manley, Manuel S. Romero-Cano, Marinova, Marmur, Maroto, McGown, Meakin, Meesters, Melik, Melik, Morales, Mulholland, Osorio, Pashley, Peula, Poulin, Prieve, Provencher, Puertas, Puertas, Puertas, Reddy, Reering, Rojas, Rojas, Romero-Cano, Romero-Cano, Rubio-Hernández, Russel, Sakai, Sakai, Salager, Salager, Sandkühler, Schmitt, Schmitt, Schmitt, Shinoda, Solè, Sonntag, Spielman, Stachurski, Stanislav, Sun, Sun, Tabor, Taylor, Toro-Mendoza, Urbina-Villalba, Urbina-Villalba, Urbina-Villalba, Urbina-Villalba, Urbina-Villalba, Urbina-Villalba, Urbina-Villalba, Urbina-Villalba, Urbina-Villalba, van de Ven, van den Tempel, Velikov, Verbich, Verwey, Verwey, Vicsek, von Smoluchowski, von Smoluchowski, Wagner, Wang, Wang, Wang, Weers, Weiss, Weitz, Xu, Young, Yu   +151 more
core   +1 more source