Results 91 to 100 of about 304,857 (302)

Soil structure stability and distribution of carbon in water-stable aggregates in different tilled and fertilized Haplic Luvisol

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2012
The influence of tillage and fertilization on soil structure stability and the distribution of carbon in water-stable aggregates of loamy Haplic Luvisol were studied.
Vladimír Šimanský
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

The dynamics of soil aggregate breakdown in water in response to landuse as measured with laser diffraction technique [PDF]

The Mastersizer 2000G (Malvern Instruments) Diffraction Instrument was used to assess and quantify the breakdown of soil aggregates and compute wet aggregate stability indices.
Oyedele, Durodoluwa J., Pini, Roberto, Scatena, Michele, Sparvoli, Enzo   +3 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Medium-term Impact of Conservation Agriculture on Soil Organic Carbon and Water Stable Aggregates in a Rainfed Hilly Agro-ecosystem

International Journal of Bio-Resource and Stress Management, 2023
The impact of conservation agriculture production system (CAPS) on soil organic carbon, bulk density, water stable aggregates and dry season soil moisture content across the profile (0−5, 5−10 and 10−20 cm) was assessed at the end of the 3rd cropping ...
K. N. Mishra, Bidyashree Tripathy, P. K. Roul, S. N. Dash   +3 more
doaj  

Extraction of Heavy Metals from Water-Stable Soil Aggregates Using EDTA

Procedia Environmental Sciences, 2013
AbstractSurface soil samples (0-15cm) were collected from a lead/zinc tailing site in Nanjing, China, and separated into four size fractions of water-stable aggregates. Metal contents in the bulk soil were 7479±370 mg·kg-1 for Zn, 4189±82 mg·kg-1 for Pb, 58.0±0.4 mg·kg-1 for Cd and 544±22mg·kg-1 for Cu, respectively.
Ding, Zhuhong, Wang, Quyi, Hu, Xin
openaire   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Soil structure and aggregate stability of A-horizons in different soil types across the Nitra Valley slope, western Slovakia

Geographia Polonica
The aim of the study was to identify the impact of the basic soil properties and slope inclination on the distribution and stability of water-stable aggregates in three different land uses (deciduous forest, vineyard, arable soil) across three soil types
Bogusława Kruczkowska, Edyta Regulska, Martin Juriga, Michał Jankowski, Maciej Markiewicz, Vladimir Šimanský   +5 more
doaj   +1 more source

Soil Organic-Matter in Water-Stable Aggregates Under Different Soil-Management Practices

Agriculture, 2017
An experiment of different management practices in a commercial vineyard, which was established in 2006 in the locality of Nitra-Dražovce, Slovakia on Rendzic Leptosol, was used to evaluate the dynamics of soil organic-matter parameters during the years ...
Šimanský Vladimír, Horák Ján, Clothier Brent, Buchkina Natalya, Igaz Dušan   +4 more
doaj   +1 more source