Results 131 to 140 of about 13,072,871 (281)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Water Activity Governs Ice Nanocrystal Evolution in Rapidly Frozen Sugar Solutions. [PDF]

J Phys Chem Lett
Kumada T, Nakabe R, Nakagawa H, Hirata Y, Mochizuki T, Motokawa R, Kodama K, Hiroi K, Oku T, Ohishi K, Morikawa T, Kawamura Y, Kawai K, Suzuki Y.   +13 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Combined effects of heat and rhamnolipids against Listeria monocytogenes: Influence of water activity and pH. [PDF]

World J Microbiol Biotechnol
Gomes GV, Nitschke M.
europepmc   +1 more source

Single-cell analysis in hypersaline brines predicts a water-activity limit of microbial anabolic activity. [PDF]

Sci Adv, 2023
Paris ER, Arandia-Gorostidi N, Klempay B, Bowman JS, Pontefract A, Elbon CE, Glass JB, Ingall ED, Doran PT, Som SM, Schmidt BE, Dekas AE.   +11 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Distribution and Genome Epidemiological Characteristics of <i>Salmonella</i> Isolates in Low Water Activity Foods. [PDF]

Foods
Zhou F, Xu M, Liu X, An Y, Deng J, Lin X, Wang W, Wang Q.   +7 more
europepmc   +1 more source

Influence of pine and miscanthus biochar on the water activity and moisture sorption isotherms of used broiler litter. [PDF]

Heliyon, 2023
Linhoss JE, Mohammadi-Aragh MK, Evans JD.   +2 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Analytical Prediction of Water Activity Evolution for Shelf Life Modeling of Packaged Dehydrated Foods. [PDF]

J Food Sci
Giannakourou M, Semenoglou I, Dermesonlouoglou E, Taoukis P.   +3 more
europepmc   +1 more source