Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
An Optical Reporting Patch for Spatiotemporal Measurements of Water Activity in Complex Environments. [PDF]
Wu IF +6 more
europepmc +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Growth of microorganisms in a Martian regolith simulant at reduced water activity. [PDF]
Raghavendra JB +2 more
europepmc +1 more source
Effect of Water Activity, pH, and Lactic Acid Bacteria to Inhibit Escherichia coli during Chihuahua Cheese Manufacture. [PDF]
Chacón-Flores NA +4 more
europepmc +1 more source
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Synergistic Regulation of Water Activity and Ion Transport by an In Situ-Grown MOF/Bacterial Cellulose Separator for High-Performance Zn Anodes. [PDF]
Fu C, Wang J, Huang W, Ren W, Wang S.
europepmc +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Redefining Separator Design and Water Activity for High-Energy Zinc Batteries Using Covalent Organic Framework. [PDF]
Zhang K +12 more
europepmc +1 more source
Dynamics of Active Fluorescent Units (AFU) and Water Activity (a<sub>w</sub>) Changes in Probiotic Products-Pilot Study. [PDF]
Sielatycka K +7 more
europepmc +1 more source

