Results 101 to 110 of about 1,276,993 (309)

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Overcoming the Fear of Water at the Initial Stage of Learning to Swim

open access: yesФізичне виховання, спорт і культура здоров’я у сучасному суспільстві, 2017
The article deals with the fear of children of primary school age to open water, which appears at the initial stage of teaching swimming and is a serious obstacle to mastering the skills of swimming.
Olga Obrazhey
doaj   +1 more source

Hyporheic hydraulic geometry: Conceptualizing relationships among hyporheic exchange, storage, and water age. [PDF]

open access: yesPLoS One, 2022
Poole GC   +7 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Governance of a complex system: water [PDF]

open access: yes, 2014
This paper sets out a complex adaptive systems view of water governance. Overview Fresh water is a life - enabling resource as well as the source of spiritual, social and economic wellbeing and development.
Elizabeth Eppel, Eppel, Elizabeth
core  

Trial by Water through the Ages

open access: yesSTUDIA ANTIQUA ET ARCHAEOLOGICA, 2021
The concept of trial by water or water ordeal is best known to the wider public through European witch trials from the Late Middle Ages and the Early Modern Period, but the practiced is first attested in near eastern texts from the Middle Bronze Age (2200–1550 BCE). The depiction of the medieval trials is largely folkloric, such trials were nonetheless
openaire   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Water-Resources Investigations Report 80-16

open access: yes, 1980
: Sediments of Cretaceous to Holocene age compose the Northern Atlantic Coastal Plain aquifer system in an area of 50,000 square miles from North Carolina to New York. The aquifer system is the principal source of water supply for most of the area. About
Meisler, Harold
core  

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