Results 51 to 60 of about 463,394 (315)

Sediment coarsening in the Yellow River subaqueous delta: Regional patterns, causes, and implications

open access: yesInternational Journal of Sediment Research
Sediment coarsening in submerged deltas is commonly attributed to seabed erosion because of insufficient sediment input. The Yellow River subaqueous delta (YRSD) has exhibited distinct coarsening patterns following both accretion and erosion events.
Yaoshen Fan   +9 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Bahr Yousef meandering canal management – Hydraulic and morphological assessment

open access: yesWater Science
Bahr Yousef is a meandering earthen canal and is considered one of the most morphologically active semi-natural streams in the west of River Nile region in Egypt.
Basma Samir Radi Awad   +5 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Aquaporin Water Channels and Hydrocephalus

open access: yesPediatric Neurosurgery, 2016
The aquaporins (AQPs) are a family of water-transporting proteins that are broadly expressed in mammalian cells. Two AQPs in the central nervous system, AQP1 and AQP4, might play a role in hydrocephalus and are thus potential drug targets. AQP1 is expressed in the ventricular-facing membrane of choroid plexus epithelial cells, where it facilitates the ...
Alan S, Verkman   +3 more
openaire   +3 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

The driving factors of water use and its decoupling relationship with economic development—A multi-sectoral perspective in the nine provinces of the Yellow River Basin

open access: yesJournal of Hydrology: Regional Studies
Study region: Yellow River Nine Provinces (China) Study focus: This study analyzes water consumption drivers in agriculture, industry, and domestic sectors using the LMDI method. It explores the relationship between water use and economic development via
Shengqi Jian   +3 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Role of Aquaporins in the Physiological Functions of Mesenchymal Stem Cells

open access: yesCells, 2020
Aquaporins (AQPs) are a family of membrane water channel proteins that control osmotically-driven water transport across cell membranes. Recent studies have focused on the assessment of fluid flux regulation in relation to the biological processes that ...
Antonella Zannetti   +5 more
doaj   +1 more source

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