Results 61 to 70 of about 1,624,308 (352)

Aquaporins in Cancer Biology

Frontiers in Oncology, 2022
Aquaporins (AQPs) are a family of transmembrane water channel proteins, which were initially characterized as a novel protein family that plays a vital role in transcellular and transepithelial water movement.
Chul So Moon, Chul So Moon, David Moon, David Moon, Sung Koo Kang, Sung Koo Kang   +5 more
doaj   +1 more source

Quick appraisal of "Sistema de suministro desde el embalse del Cenajo a la Mancomunidad de Canales del Taibilla" [PDF]

, 2013
The project under assessment concerns the construction of an aqueduct in order to divert water from Tajo-Segura Channel onto the Cenajo reservoir and to the water purification plants of Sierra de la Espada and of Campotéjar.
COWI, Directorate-General for Regional and Urban Policy (European Commission)   +1 more
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Influence of precipitation and runoff on human-induced land subsidence in the Yellow River Delta

Quaternary Science Advances
Land subsidence in river deltas, particularly in the Yellow River Delta (YRD), represents an urgent environmental concern driven by both human activities and natural factors.
Yaoshen Fan, Guangzhou Wang, Shentang Dou, Chao Jiang, Hongyu Ji, Shenliang Chen, Xiaokang Du, Shoubing Yu, Yan Wu, Shaohua Zhang   +9 more
doaj   +1 more source

Aquaporins: The renal water channels

Indian Journal of Nephrology, 2008
Water is the most abundant molecule in any cell. Specialized membrane channel, proteins called aquaporins, facilitate water transport across cell membranes. At least seven aquaporins (AQP): 1, 2, 3, 4, 6, 7, and 11 are expressed in the kidneys. Aquaporins play a role in both the short-term and long-term regulation of water balance as well as in the ...
Agarwal, S. K., Gupta, A.
openaire   +2 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Sediment coarsening in the Yellow River subaqueous delta: Regional patterns, causes, and implications

International Journal of Sediment Research
Sediment coarsening in submerged deltas is commonly attributed to seabed erosion because of insufficient sediment input. The Yellow River subaqueous delta (YRSD) has exhibited distinct coarsening patterns following both accretion and erosion events.
Yaoshen Fan, Guangzhou Wang, Shentang Dou, Hongyu Ji, Weiming Xie, Peng Li, Xiaokang Du, Shoubing Yu, Shaohua Zhang, Chao Zhu   +9 more
doaj   +1 more source

Role of Aquaporins in the Physiological Functions of Mesenchymal Stem Cells

Cells, 2020
Aquaporins (AQPs) are a family of membrane water channel proteins that control osmotically-driven water transport across cell membranes. Recent studies have focused on the assessment of fluid flux regulation in relation to the biological processes that ...
Antonella Zannetti, Gheorghe Benga, Arturo Brunetti, Francesco Napolitano, Luigi Avallone, Alessandra Pelagalli   +5 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source