Results 91 to 100 of about 873,686 (310)
Modelling Techniques in Dynamic Control of Water Distribution Systems
Measurement + Control, 1978 The paper outlines the major requirements for dynamic control of water distribution systems and presents a control scheme which will ensure optimal operation.
B Coulbeck, M. J. H. Sterling
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Comparison of simplified methods for the optimisation of water distribution systems
, 2012 Evolutionary algorithms have been applied for the last 20 years to find near-optimal designs of water distribution systems (WDS). However, they suffer the disadvantage that they require a significant amount of computer time, especially for water ...
Dandy, G., Marchi, A.
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An Innovative Approach for Water Distribution Systems [PDF]
Intelligent Automation & Soft Computing, 2022 Van-Phuong Ta +2 more
openaire +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Effects of geometry on hydraulic reliability of water distribution systems
, 2010 The reliability of water distribution networks relates to two types of failure: mechanical failure of system components and hydraulic failure caused by changes in demand and pressure head.
Bang, S.
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A water supply-based optimization model for water distribution in two-level canal systems
Guan'gai paishui xuebao【Objective】 Optimizing water distribution in canal-irrigation districts is a prerequisite to improve irrigation water use efficiency. This paper proposes an optimization method to distribute water in two-level canal-irrigation systems.
FAN Yu +6 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Optimization of the water distribution network flushing [PDF]
, 2021 Ispiranje vodovodne mreže se sprovodi nakon što se za određeni deo mreže, ili zone za ispiranje, ustanovi da je voda izložena visokom riziku od zamućenja (promene boje).
Ivetić, Damjan, Vasilić, Željko
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