Results 71 to 80 of about 6,542 (216)
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
A water supply-based optimization model for water distribution in two-level canal systems
Guan'gai paishui xuebao【Objective】 Optimizing water distribution in canal-irrigation districts is a prerequisite to improve irrigation water use efficiency. This paper proposes an optimization method to distribute water in two-level canal-irrigation systems.
FAN Yu +6 more
doaj +1 more source
Cartagena's Water Distribution System
Procedia Engineering, 2017 Abstract Cartagena's Water Distribution System serves almost one million inhabitants. The raw water that feeds the system is collected 40 km from the city, and it is transported by series of pumping stations to El Bosque Water Treatment Plant (WTP). From this place, the water is conveyed to 10 District Meter Areas (DMAs) working under the scheme 24/7
Fredy Angulo +3 more
openaire +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
An optimal water distribution model for canal systems based on water level
Scientific ReportsThis paper presents an optimal water distribution model for canals that focuses on canal flow capacity as a foundational premise. The model aims to optimize the flow rate and timing of irrigation to satisfy the water demands necessary for crop growth ...
Ke Zhou +5 more
doaj +1 more source
An Innovative Approach for Water Distribution Systems [PDF]
Intelligent Automation & Soft Computing, 2022 Van-Phuong Ta +2 more
openaire +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Robust adaptive optimization for sustainable water demand prediction in water distribution systems
Scientific ReportsThe advancement of the Internet of Things has positioned intelligent water demand forecasting as a critical component in the quest for sustainable water resource management.
Ke Wang +4 more
doaj +1 more source
Известия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2016 The method of calculation of economic efficiency that can be universal and is suitable for feasibility study of modernization of irrigation and water distribution system of cooling towers has been developed.
Yu. A. Zenovich-Leshkevich-Olpinskiy +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source