Results 51 to 60 of about 873,686 (310)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Development of a Multi-Objective Optimal Design Approach for Combined Water Systems

open access: yesApplied Sciences, 2023
Recently, due to extreme climate change, damage from flooding has been increasing; however, water shortages are being announced simultaneously. Moreover, the water distribution system’s ability to supply consumers is being overwhelmed because of ...
Mun Jin Ko, Young Hwan Choi
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Fluorescence-informed water quality prediction in water distribution systems

open access: yesUrban Lifeline
Conventional drinking water monitoring relies on laboratory-based chemical and microbiological analyses that are often time intensive. This study evaluates a rapid optical alternative by integrating excitation–emission matrix (EEM) fluorescence ...
Yi Xu, Mohamad Zeidan, Nicolas Peleato
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Water consumption time series forecasting in urban centers using deep neural networks

open access: yesApplied Water Science
The time series analysis and prediction techniques are highly valued in many application fields, such as economy, medicine and biology, environmental sciences or meteorology, among others. In the last years, there is a growing interest in the sustainable
C. G. García-Soto   +4 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Reliability-based optimal design of water distribution networks

open access: yes, 2001
A considerable amount of research has been carried out on the reliability analysis and optimal design of water distribution systems, and it has been reported that each of the above problems is very difficult to solve (Eiger et al.
Xu, C.   +3 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Operating Water Distribution Systems for Equitable Access to Clean Water

open access: yesEngineering Proceedings
Water distribution systems (WDSs) are designed to deliver potable water across urban areas. Unpredicted changes in water demands and hydraulics can increase the residence time in pipes, leading to the growth of microbes and decreased water quality at ...
Brent Vizanko   +4 more
doaj   +1 more source

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