Results 91 to 100 of about 3,040,620 (306)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Stages of planning measures for engineering and environmental protection of water bodies – drainage water inlets from irrigated lands

open access: yesМелиорация и гидротехника
Purpose: to develop the main stages of planning the measures of engineering and environmental protection of water bodies – drainage water inlets from irrigated lands. Materials and methods.
Tatyana I. Drovovozova   +2 more
doaj   +1 more source

Wireless ICS Training Platform [PDF]

open access: yes, 2019
Indiana University - Purdue University IndianapolisEssential public services, such as Electric, Water and Gas Utilities, are becoming increasingly reliant on network connected devices to control their processes. Wireless control systems are becoming more
Cassandra Boman, Nick Pohlman
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Co-engineering Participatory Water Management Processes: Theory and Insights from Australian and Bulgarian Interventions

open access: yesEcology and Society, 2010
Broad-scale, multi-governance level, participatory water management processes intended to aid collective decision making and learning are rarely initiated, designed, implemented, and managed by one person.
Katherine A. Daniell   +11 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

An Interdisciplinary Approach for the Assessment and Implementation of Resilient and Flexible Water Supply Infrastructure under Changing or Instable Conditions [PDF]

open access: yes, 2015
In case of demographic changes or emergencies pipeline bound infrastructure like gas or water is specifically challenged. Then, the advantages of decentralized infrastructure should be considered: Minimization of asset bound funds; flexibility ...
Günthert, F.W., Walter, W.K.
core  

Control of Surface Wettability via Strain Engineering

open access: yes, 2013
Reversible control of surface wettability has wide applications in lab-on-chip systems, tunable optical lenses, and microfluidic tools. Using a graphene sheet as a sample material and molecular dynamic (MD) simulations, we demonstrate that strain ...
Liu, Jefferson Zhe   +3 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy