Results 81 to 90 of about 3,040,620 (306)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Is there progress in the adsorbent development for water treatment?
iScienceSummary: Adsorption technology is an essential part of modern water treatment. However, only a handful of adsorbent materials are used industrially, which is in striking contrast with the exponentially increasing scientific publishing activity.
Tero Luukkonen, Juhani Teeriniemi
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Exclusion zone phenomena in water -- a critical review of experimental findings and theories
, 2020 The existence of the exclusion zone (EZ), a layer of water in which plastic microspheres are repelled from hydrophilic surfaces, has now been independently demonstrated by several groups.
Elton, Daniel C. +3 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Men, Masculinities and Water Powers in Irrigation [PDF]
, 2008 The aim of this article is to provide an informed plea for more explicitly identifying, naming and unravelling the linkages between water control and gender in irrigation.
Zwarteveen, M.Z.
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Water Quality System Informatics: An Emerging Inter-Discipline of Environmental Engineering
EngineeringWater quality system informatics (WQSI) is an emerging field that employs cybernetics to collect and digitize data associated with water quality. It involves monitoring the physical, chemical, and biological processes that affect water quality and the ...
Hong Liu +6 more
doaj +1 more source
Measurement of groundwater dewatering in excavations in Tianjin
Yantu gongcheng xuebao, 2019 Based on the characteristics of engineering geology and hydrogeological characteristics in Tianjin, multiple excavation dewatering projects are monitored comprehensively in the entire process.
DIAO Yu 1, 2, GAO Ze-dong 1, 2, ZHENG Gang 1, 2, CHU Zhen-xi 1, 2, GUO Yong-zhi 1, 2, JIA Zhen-yang 1, 2
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source