Results 61 to 70 of about 372,230 (299)
Numerical Investigation on the Water Entry of Several Different Bow-Flared Sections
Applied Sciences, 2020 The bow-flared section may be simplified in the prediction of slamming loads and whipping responses of ships. However, the difference of hydrodynamic characteristics between the water entry of the simplified sections and that of the original section has ...
Qiang Wang +4 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Shock and Vibration, 2022 In this study, the water entry of an air-launched underwater glider under wave conditions is numerically simulated by the computational fluid dynamics method.
Xiangcheng Wu +5 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Business Environment and Firm Entry: Evidence from International Data [PDF]
Using a comprehensive database of firms in Western and Eastern Europe, we study how the business environment in a country drives the creation of new firms. Our focus is on regulations governing entry. We find entry regulations hamper entry, especially in
Raghuram Rajan +2 more
core +2 more sources
BrodogradnjaIn this paper, the slamming loads and structural response of an aluminium flat stiffened-plate structure during calm water entry considering the hydroelasticity effects are studied by a partitioned CFD-FEM two-way coupled method.
Jialong Jiao, Zhenwei Chen, Sheng Xu
doaj +1 more source
Water Entry of A Wedge Into Waves in Three Degrees Offreedom
Polish Maritime Research, 2019 The hydrodynamic problem of a two-dimensional wedge entering into a nonlinear wave in three degrees of freedom is investigated based on the incompressible velocity potential theory.
Sun Shi Yan, Chen Hai Long, Xu Gang
doaj +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source