Results 101 to 110 of about 231,198 (267)

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

TRPML1-Induced Lysosomal Ca²⁺ Signals Activate AQP2 Translocation and Water Flux in Renal Collecting Duct Cells. [PDF]

Int J Mol Sci, 2023
Scorza SI, Milano S, Saponara I, Certini M, De Zio R, Mola MG, Procino G, Carmosino M, Moccia F, Svelto M, Gerbino A.   +10 more
europepmc   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Tutorial for Stopped-Flow Water Flux Measurements: Why a Report about "Ultrafast Water Permeation through Nanochannels with a Densely Fluorous Interior Surface" Is Flawed. [PDF]

Biomolecules, 2023
Pfeffermann J, Pohl P.
europepmc   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Time variation flow model of reservoir permeability based on effective cumulative water flux

Youqi dizhi yu caishoulu
The permeability of high water-cut reservoirs will change during long-term water flooding. The traditional parameters characterizing water flooding do not consider the influence of critical flow velocity when describing the time variation law of ...
ZHANG Rui, WANG Tao, WANG Fei, ZHU Xuchen, WANG Yanhong, KOU Shuangyan, WANG Jing   +6 more
doaj   +1 more source

Biofouling-Resistant Ultrafiltration Membranes via Codeposition of Dopamine and Cetyltrimethylammonium Bromide with Retained Size Selectivity and Water Flux. [PDF]

ACS Appl Mater Interfaces, 2022
Cihanoğlu A, Schiffman JD, Alsoy Altinkaya S.   +2 more
europepmc   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Combined Evaporation and Energy Balance of Upper and Lower Reservoirs in Pumped Storage Power Stations in Arid Regions

Hydrology
This study takes the pumped hydro storage (PHS) in arid areas—where the irrigation reservoir in the piedmont plain serves as the lower reservoir—as the research object.
Xin Lei, Ke-Wu Han, Fei He, Xian Cheng, Hai-Bo Jiang   +4 more
doaj   +1 more source

Synthesis of PNIPAAm-g-P4VP Microgel as Draw Agent in Forward Osmosis by RAFT Polymerization and Reverse Suspension Polymerization to Improve Water Flux. [PDF]

Molecules, 2022
Gao Y, Yao X, Jiang Q, Liao J, Chen Y, Yu R.   +5 more
europepmc   +1 more source