Results 161 to 170 of about 7,416,707 (356)

Water Flux Prediction in Direct Contact Membrane Distillation Subject to Inorganic Fouling. [PDF]

Membranes (Basel), 2022
Suárez F, Del Río MB, Aravena JE.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

TRPML1-Induced Lysosomal Ca²⁺ Signals Activate AQP2 Translocation and Water Flux in Renal Collecting Duct Cells. [PDF]

Int J Mol Sci, 2023
Scorza SI, Milano S, Saponara I, Certini M, De Zio R, Mola MG, Procino G, Carmosino M, Moccia F, Svelto M, Gerbino A.   +10 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Water-wise Rice Production

, 2002
Rice is a profligate user of water. It takes 3,000–5,000 liters to produce 1 kilogram of rice, which is about 2 to 3 times more than to produce 1 kilogram of other cereals such as wheat or maize.
Hengsdijk, H., Bindraban, P.S., Ladha, J.K., Hardy, B., Tuong, T.P., Bouman, B.A.M.   +5 more
core  

Tutorial for Stopped-Flow Water Flux Measurements: Why a Report about "Ultrafast Water Permeation through Nanochannels with a Densely Fluorous Interior Surface" Is Flawed. [PDF]

Biomolecules, 2023
Pfeffermann J, Pohl P.
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Variability of water masses and circulation in the subtropical North Atlantic [PDF]

, 1999
Observations of interannual variability in 18 Water (Talley and Raymer 1982) and Gulf Stream transport (Worthington 1977) motivate an ocean model sensitivity study. The North Atlantic circulation is simulated with a three-dimensional isopycnic coordinate
Marsh, R.
core  

Time variation flow model of reservoir permeability based on effective cumulative water flux

Youqi dizhi yu caishoulu
The permeability of high water-cut reservoirs will change during long-term water flooding. The traditional parameters characterizing water flooding do not consider the influence of critical flow velocity when describing the time variation law of ...
ZHANG Rui, WANG Tao, WANG Fei, ZHU Xuchen, WANG Yanhong, KOU Shuangyan, WANG Jing   +6 more
doaj   +1 more source

Biofouling-Resistant Ultrafiltration Membranes via Codeposition of Dopamine and Cetyltrimethylammonium Bromide with Retained Size Selectivity and Water Flux. [PDF]

ACS Appl Mater Interfaces, 2022
Cihanoğlu A, Schiffman JD, Alsoy Altinkaya S.   +2 more
europepmc   +1 more source