Results 61 to 70 of about 231,198 (267)
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
MembranesConcentration polarization (CP) is one of the inherent problems that lowers the operating performance of forward osmosis (FO) membranes. Therefore, a quantitative evaluation of CP is vital to understand its impact on the FO process.
Ping Xiao, Liang Liu
doaj +1 more source
Investigation of Methanol Crossover and Water Flux in an Air-Breathing Direct Methanol Fuel Cell
International Journal of Electrochemical Science, 2015 An air-breathing direct methanol fuel cell (DMFC) is constructed to investigate methanol crossover and water flux by altering flow rate and concentration of methanol solution.
Qi Wang +5 more
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Beyond ion homeostasis: WNK1 and the role of water influx in T cell biology
Frontiers in ImmunologyThe serine-threonine kinase WNK1 is a regulator of ion homeostasis and cell volume control studied most extensively in the kidney. WNK1 phosphorylates and activates the OXSR1 and STK39 kinases, which in turn phosphorylate members of the SLC12A-family of ...
Robert Köchl, Victor L. J. Tybulewicz
doaj +1 more source
Comparative Study for Organic and Inorganic Draw Solutions in Forward Osmosis
Al-Khawarizmi Engineering Journal, 2017 The present work aims to study forward osmosis process using different kinds of draw solutions and membranes. Three types of draw solutions (sodium chloride, sodium formate, and sodium acetate) were used in forward osmosis process to evaluate their ...
Ahmed Faiq Al-Alalawy +2 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source