Results 131 to 140 of about 28,076 (308)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Agricultural water markets: exploring limits and opportunities in Italy and Spain [PDF]
Agriculture is the main water-using sector in Southern European Countries, such as Spain and Italy. Innovative institutional solutions for reducing water use or increasing its efficiency are pursued by recent legislation concerning water, in particular ...
Joan Pujol, Davide Viaggi, Meri Raggi
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Water Policy and Sustainability of Irrigated Farming Systems in Italy
The objective of this paper is to provide an analysis of the sustainability of irrigated agriculture in Italy in the context of CAP reform and Water Framework Directive.
Viaggi, Davide +4 more
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Cost-Benefit Analysis in a Framework of Stakeholder Involvement and Integrated Coastal Zone Modeling [PDF]
Active involvement of local stakeholders is currently an increasingly important requirement in European environmental regulations such as the EU Water Framework Directive (WFD) and the EU Marine Strategy Framework Directive (MSFD).
Söderqvist, Tore +4 more
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Practical Experiences from Existing Case Studies and Pilot River Basins
, 2010 Water resources planning and management and the development of appropriate policies requires methodologies and tools that are able to support systematic, integrative and multidisciplinary assessments at various scales. It also requires the quantification
Hatterman, F.F +11 more
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Assessing water pricing policies to enhance water efficiency in agriculture [PDF]
, 2010 The improvement of water use efficiency is one of the priorities of the Water Framework Directive 2000/60/EC. In order to pursue this objective, the European Union suggests member countries adopt a direct pricing method, in which each user is charged ...
Giacomo Zanni +6 more
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New directions in water resources management: The role of water pricing policies
, 2008 Water resources will face increasing competition and higher environmental concerns during this century. To meet these challenges, the new Water Framework Directive has drawn up an integrated framework and established the basic principles for a ...
Blanco Fonseca, Maria +1 more
core +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source