Results 61 to 70 of about 9,963,926 (282)

The Water Framework Directive: A New Directive for a Changing Social, Political and Economic European Framework [PDF]

European Planning Studies, 2003
This article examines the intricate process of developing the European Union's Water Framework Directive. It sees the Directive as a response to recent economic, political and social changes related to water management, including the shift from government to governance, the liberalization of water markets and the emergence of a new set of institutions,
openaire   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Proposal of a Python interface to OpenMI, as the base for open source hydrological framework

Geoinformatics FCE CTU, 2012
Hydrologists need simple, yet powerful, open source framework for developing and testing mathematical models. Such framework should ensure long-term interoperability and high scalability. This can be done by implementation of the existing, already tested
Robert Szczepanek
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Retrieval of Chlorophyll a from Sentinel-2 MSI Data for the European Union Water Framework Directive Reporting Purposes

Remote Sensing, 2018
The European Parliament and The Council of the European Union have established the Water Framework Directive (2000/60/EC) for all European Union member states to achieve, at least, “good” ecological status of all water bodies larger than 50 ...
Ave Ansper, Krista Alikas
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

A typology of stakeholders and guidelines for engagement in transdisciplinary, participatory processes

Frontiers in Marine Science, 2016
This paper presents a typology of stakeholders for effective participatory processes and co-design of solutions to complex social-environmental issues and a roadmap stepwise methodology for balanced and productive stakeholder engagement.
Alice Newton, Alice Newton, Michael Elliott   +2 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Law policy of European Union in the sphere of water conservation

Проблеми Законності, 2017
In the light of such foreign policy goal as accession to the EU there was arised a need to thorough research of European Union’s water policy and legislation with the view of its adaptation to the national legislation. The basic issues of European Union’
Марина Костянтинівна Черкашина
doaj   +1 more source