Gender, Social Capital and Collective Action: A gender perspective on collective sustainability of water resource governance in west Nepal [PDF]
In Nepal, as in other South Asian countries, water resource development is often considered to be a primarily technological challenge, requiring engineered solutions.
Clement, Floriane, Shrestha, Gitta
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
The environment as a challenge for governmental responsibility: The case of the European Water Framework Directive [PDF]
The European Water Framework Directive is shaping a new conception of integrative water protection. In this article, the consequences of the Water Framework Directive in respect to national environmental policy will be discussed in referring to the ...
Klauer, Bernd +2 more
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Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Gendered Social Norms Change in Water Governance Structures Through Community Facilitation: Evaluation of the UPWARD Intervention in Tanzania. [PDF]
Eaton J +7 more
europepmc +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Implementing integrated river basin management: lessons from the Red River Basin, Vietnam [PDF]
River basin management / Water resource management / Legal aspects / Water law / Water policy / Institutional reform / Organizational change / Institutions / Governance / Development projects / Participatory management / Vietnam / Red River Basin / Cau ...
Hoanh, Chu Thai, Molle, Francois
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The potential role of socio-hydrological models for participatory water governance in Burkina Faso [PDF]
Halting and reversing water quality degradation is a major global concern. The variety of needs and priorities placed on water resources make the issue of water pollution multifaceted and complex.
Barendrecht, Marlies +2 more
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
: Due to uneven networked water coverage in the Global South, varied water infrastructures operate beyond utility networks to serve denizens in Global South cities.
Francis Dakyaga +3 more
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