Results 71 to 80 of about 1,507,587 (278)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Microbubbles enhanced synthetic phorbol ester degradation by ozonolysis [PDF]
, 2014 A phorbol-12-myristate-13-acetate (TPA) is a synthetic analogue of phorbol ester (PE), a natural toxic compound of Euphorbiaceae plant. The oil extracted from plants of this family is useful source for primarily biofuel.
Kuvshinov, Dmitriy +2 more
core +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The effect of water injection on nitric oxide emissions of a gas turbine combustor burning ASTM Jet-A fuel [PDF]
Tests were conducted to determine the effect of water injection on oxides of nitrogen (NOx) emissions of a full annular, ram induction gas turbine combustor burning ASTM Jet-A fuel.
Diehl, L. A. +2 more
core +1 more source
Assessing impacts to groundwater from CO2-flooding of SACROC and Claytonville oil fields in West Texas [PDF]
, 2006 Comparison of groundwater above two Permian Basin oil fields (SACROC Unit and Claytonville Field) near Snyder, Texas should allow us to assess potential impacts of 30 years of CO2-injection.
Guillot, Stephen N. +2 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
JGEET: Journal of Geoscience, Engineering, Environment and Technology, 2023 This research provides the scenario of a field development plant with the primary goal of acknowledging the reservoir model of Kappa Field in determining the optimum field development scenario to increase the recovery factor.
Iwan Setya Budi +1 more
doaj
Numerical Analysis of NOx Reduction Using Ammonia Injection and Comparison with Water Injection
Journal of Marine Science and Engineering, 2020 This work analyzes NOx reduction in a marine diesel engine using ammonia injection directly into the cylinder and compares this procedure with water injection. A numerical model based on the so-called inert species method was applied.
María Isabel Lamas Galdo +2 more
doaj +1 more source
Ignition overpressure study from solid rocket motor firings [PDF]
The objective was to investigate, through experimental means, the basic mechanisms influencing ignition overpressure and to determine ways to suppress ignition overpressure. Ignition overpressure was studied using solid rocket motors with geometry scaled
Counter, Douglas D.
core +1 more source