Results 131 to 140 of about 2,609,914 (372)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Groundwater Quality Index for Water Supply Production [PDF]

EnvironmentAsia, 2013
Groundwater quality index for water supply production, GWQI, was employed as a simple mathematical tool to integrate the complex groundwater quality data into a numerical score. It would guide to select an appropriate water supply treatment process.
Warangkana Sungsitthisawad, Somsak Pitaksanurat   +1 more
doaj  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

A Study on the Utility of Electrical Conductivity as an Index of Quality of Irrigation Water [PDF]

, 1965
Rajasekar Krishnamurthy
openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Correlation of various water quality parameters and water quality index of districts of Uttarakhand

Environmental and Sustainability Indicators, 2021
This study is based on hydrogeochemical and biological parameters and calculation of Water Quality Index (WQI) to assess water quality of a rural tract in five districts of Garhwal and Kumaon district of Uttarakhand, India.
Vinod Kothari, Suman Vij, SuneshKumar Sharma, Neha Gupta   +3 more
doaj  

Evaluation of water quality index of the river Cauvery and its tributaries [PDF]

, 1997
Water quality of the river Cauvery and its tributaries - Arkavathi and Vrishabhavathi - was assessed by using Bhargava's water quality index. Significant seasonal variation was revealed by the spatially measured physico-chemical characteristics.
Chetana Suvarna, A., Somashekar, R.K.
core  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Index of streamflow and water quality records to September 30, 1978, south-central Alaska [PDF]

, 1980
Patsy J. Still
openalex   +1 more source

Application of Water Quality Index for the assessment of water quality of lakes

The specific physio-chemical and biological characteristics of water determine its suitability for various purposes, including domestic, agricultural and industrial use, highlighting the importance of complete chemical analysis. An attempt is made to understand the water quality of selected lakes in and around Bangalore.
Amritha Thankachan, Dr. M. Inayathulla
openaire   +1 more source