Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Improving Water Quality Index Prediction Using Regression Learning Models. [PDF]
Int J Environ Res Public Health, 2022 Mohd Zebaral Hoque J +4 more
europepmc +1 more source
Evaluation of a Number of Water Treatment Plants in Kirkuk Governorate using the Water Quality Index [PDF]
, 2018 Rodhan Abdullah Salih +2 more
openalex +1 more source
Water Quality of Boalia Khal Tributary of Halda River by Weighted Arithmetic Index Method [PDF]
, 2021 Md. Safiqul Islam +3 more
openalex +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Water Quality Index and Human Health Risk Assessment of Drinking Water in Selected Urban Areas of a Mega City. [PDF]
Toxics, 2023 Nawaz R +9 more
europepmc +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Integrated approach to hydrogeochemical appraisal of groundwater quality concerning arsenic contamination and its suitability analysis for drinking purposes using water quality index. [PDF]
Sci Rep, 2023 Ullah Z +9 more
europepmc +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Water quality index, ecotoxicology and human health risk modelling of surface and groundwater along illegal crude oil refining sites in a developing economy. [PDF]
Heliyon, 2023 Azuamah KO +2 more
europepmc +1 more source