Results 131 to 140 of about 957,139 (290)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Correction: Sainz et al. Analysis of Thioredoxins and Glutaredoxins in Soybean: Evidence of Translational Regulation under Water Restriction. Antioxidants 2022, 11, 1622. [PDF]

Antioxidants (Basel), 2023
Sainz MM, Filippi CV, Eastman G, Sotelo-Silveira J, Borsani O, Sotelo-Silveira M.   +5 more
europepmc   +1 more source

Cross-sectional river shapes: A variational discharge-resistance formulation [PDF]

, 1999
Cross-sectional river shapes were obtained from a variational principle: minimizing the bed friction for a given discharge and a given maximum lateral bed slope (angle of repose).
Beckum, F.P.H. van, Groesen, E. van, Roos, P.   +2 more
core   +1 more source

DISTRIBUTION OF CATTLE ON SLOPE WITHOUT WATER RESTRICTIONS

Canadian Journal of Animal Science, 1990
A study was made in the Porcupine Hills of southwestern Alberta to determine cattle distribution on slope when water is available at the top, middle, and bottom of the slope. Cows with calves were stocked at two rates (1.9 and 3.8 animal unit months (AUM) ha−1) and three replications over six small pastures in a completely random design. The study was
openaire   +2 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Effect of the application of vermicompost and millicompost humic acids about the soybean microbiome under water restriction conditions. [PDF]

Front Microbiol, 2022
da Silva MSRA, de Carvalho LAL, Braos LB, de Sousa Antunes LF, da Silva CSRA, da Silva CGN, Pinheiro DG, Correia MEF, Araújo EDS, Colnago LA, Desoignies N, Zonta E, Rigobelo EC.   +12 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

New outcomes on how silicon enables the cultivation of Panicum maximum in soil with water restriction. [PDF]

Sci Rep, 2022
Rocha JR, de Mello Prado R, de Cássia Piccolo M.   +2 more
europepmc   +1 more source

NCC restricts water supply

, 2018
Society
openaire   +2 more sources

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source