Results 121 to 130 of about 957,139 (290)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Syndrome of Inappropriate Secretion of Antidiuretic Hormone in a Dog With Meningoencephalitis of Unknown Etiology

open access: yesVeterinary Medicine and Science
A 5‐year‐old castrated male Maltese dog presented with generalized tonic‐clonic cluster seizures. The seizures first occurred 10 days prior and progressed gradually.
Yelim Lee   +5 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Analysis of Thioredoxins and Glutaredoxins in Soybean: Evidence of Translational Regulation under Water Restriction. [PDF]

open access: yesAntioxidants (Basel), 2022
Sainz MM   +5 more
europepmc   +1 more source

Study of Ardabil Drinking Water Physicochemical Parameters [PDF]

open access: yes
Background & Objectives: Ardabil city with population of about 340386 is still supplied with groundwater resource for drinking. That should have optimum quality standards in different aspects.
روح الهی, صالح   +1 more
core  

HVAC SYSTEM REMOTE MONITORING AND DIAGNOSIS OF REFRIGERANT LINE OBSTRUCTION [PDF]

open access: yes, 2018
A heating, ventilation, and air conditioning (HVAC) system of a building includes a refrigerant loop. A monitoring system for the HVAC system includes a monitoring device installed at the building.
Alsaleem, Fadi M.
core   +1 more source

Citric Acid Water Restriction v1

open access: yes, 2021
How to prepare and carry out citric acid water restriction for motivating mice to engage in behaviour.
openaire   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Seed viability of Dimorphandra gardneriana subject to water stress in different temperatures

open access: yesCiência Rural
: The forest species Dimorphandra gardneriana Tul. is widely used for various pharmacological products, yet few basic studies have been undertaken to understand their ecological and physiological attributes under stress conditions.
Marina Matias Ursulino   +6 more
doaj   +1 more source

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