Results 61 to 70 of about 6,846,870 (280)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

The Importance of Nonconventional Water Resources under Water Scarcity

Water
According to FAO, water scarcity is now affecting all five continents and is expected to intensify in the coming years as the water demands of the growing population increase and the impacts of climate variability become more pronounced.
A. Angelakis, G. Tchobanoglous, A. Capodaglio, V. A. Tzanakakis   +3 more
semanticscholar   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Exploring Global Water Scarcity Dynamics Through Causal Discovery and Structural Causal Modelling

Earth's Future
Water scarcity represents a critical global challenge driven by diverse complex interactions between natural and anthropogenic factors. Long‐term water scarcity often results in depletion of water resources in so‐called water scarcity hotspots.
Myrthe Leijnse, Marc F. P. Bierkens, Niko Wanders   +2 more
doaj   +1 more source

Key drivers and pressures of global water scarcity hotspots

Environmental Research Letters
Global freshwater resources are vital to humanity and Earth’s ecosystems, yet about one third of the global population is affected by water scarcity for at least one month per year.
Myrthe Leijnse, Marc F P Bierkens, Kim H M Gommans, D. Lin, A. Tait, N. Wanders   +5 more
semanticscholar   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Cities under pressure: a global review of acute urban water scarcity governance

Environmental Research Letters
Urban water scarcity is one of the most pressing governance challenges of our time, driven by climate change and rapid urbanization. Despite a growing body of research, scholarship remains fragmented across disciplines and regions, with the social and ...
Merel Laauwen, Johanna Koehler, Mary Greene, Dave Huitema   +3 more
doaj   +1 more source

Global agricultural economic water scarcity

Science Advances, 2020
We advance the notion of agricultural economic water scarcity to identify where irrigation expansion may increase food production. Water scarcity raises major concerns on the sustainable future of humanity and the conservation of important ecosystem ...
L. Rosa, D. Chiarelli, M. Rulli, J. Dell’Angelo, P. D’Odorico   +4 more
semanticscholar   +1 more source

Affecting the Properties of Copper–Graphene Electroconductive Composite by Severe Plastic Deformation

Advanced Engineering Materials, EarlyView.
Copper‐based composites enhanced with carbon feature convenient mechanical properties and favorable electric conductivity. Processing via deformation and thermomechanical treatments can introduce advantageous microstructures further enhancing their performance. Herein, copper–graphene powder‐based composites are directly consolidated via rotary swaging
Radim Kocich, Lenka Kunčická, Pavel Czernek, Zifan Wang   +3 more
wiley   +1 more source

Review and classification of indicators of green water availability and scarcity [PDF]

Hydrology and Earth System Sciences, 2015
Research on water scarcity has mainly focussed on blue water (ground- and surface water), but green water (soil moisture returning to the atmosphere through evaporation) is also scarce, because its availability is limited and there are competing demands ...
J. F. Schyns, A. Y. Hoekstra, M. J. Booij   +2 more
doaj   +1 more source