Results 61 to 70 of about 710,433 (307)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

In-Vitro Evaluation of Water Sorption and Solubility of G-Cem and FujiCem in Water and Acid

open access: yesJournal of Islamic Dental Association of Iran, 2013
Background and Aim: Solubility is among the negative characteristics of dental materials leading to structural degradation of cements and decreased longevity of restorations. The present study sought to assess the water sorption and solubility of FujiCem
Haleh Heshmat   +3 more
doaj  

The Bunsen gas solubility coefficient of ethylene as a function of temperature and salinity and its importance for nitrogen fixation assays [PDF]

open access: yes, 2004
The acetylene reduction assay is a common method for assessing nitrogen fixation in a variety of marine and freshwater systems. The method measures ethylene, the product of the conversion of the gas acetylene to its reduced form by nitrogenase. Knowledge
Breitbarth, Eike   +3 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

On the water-solubility of plant minerals

open access: yesAgricultural and Food Science, 1967
This paper deals with ash and mineral contents essential in the nutrition of livestock and man. The results of the investigated products are presented in Tables 1—3. Of the minerals the ash and the water-soluble part of it were determined, as well as the
Aarne Mäkelä, Kaija Kotilainen
doaj  

Diplatin, a Novel and Low-Toxicity Anti-Lung Cancer Platinum Complex, Activation of Cell Death in Tumors via a ROS/JNK/p53-Dependent Pathway, and a Low Rate of Acquired Treatment Resistance

open access: yesFrontiers in Pharmacology, 2019
Background: Platinum-based drugs prevail as the main treatment of lung cancer; this is caused by their relative effectiveness despite known side effects, such as neurotoxicity.
Xixi Lin   +16 more
doaj   +1 more source

Selective removal of H2S from sour gases with microporous membranes. Part II. A liquid membrane of water-free tertiary amines [PDF]

open access: yes, 1993
In the present study the application of a liquid membrane for selective removal of H2S from gases also containing CO2 was investigated. The liquid membrane was filled with pure methyl-di-ethanol-amine (MDEA). A theoretical model was developed to describe:
Kreulen, H.   +3 more
core   +3 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Thermodynamic Behavior of Erythromycin Thiocyanate Dihydrate in Six Pure Solvents and Two Binary Solvents

open access: yesMolecules
Thermodynamic parameters play a crucial role in analyzing and optimizing crystallization processes. In this investigation, the solubility profiles of erythromycin thiocyanate dihydrate were determined gravimetrically under atmospheric pressure (0.1 MPa ...
Jin Feng   +10 more
doaj   +1 more source

The Flux of Phenolic Compounds through Silicone Membranes

open access: yesPharmaceutics, 2013
Phenols as a class of molecules have been reported to exhibit higher log maximum fluxes through human stratum corneum, SC, from water, log JMHAQ, than other classes of molecules.
Kenneth B. Sloan, John Prybylski
doaj   +1 more source

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