Results 61 to 70 of about 2,993,457 (339)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Root exudate–assisted phytoremediation of copper and lead contamination using Rumex acetosa L. and Rumex K-1

Ecotoxicology and Environmental Safety
Heavy metal pollutants can be effectively removed from soil through phytoremediation using root exudates. Herein, experiments were conducted to assess the phytoremediation capabilities of Rumex acetosa L.
Mengfan He, Huizhen Yin, Zhuoliang Liu, Fan Luo, Xining Zhao, Huike Li, Xiaolin Song   +6 more
doaj   +1 more source

Comparative Analysis of Root Transcriptome Reveals Candidate Genes and Expression Divergence of Homoeologous Genes in Response to Water Stress in Wheat

Plants, 2020
Crop cultivars with larger root systems have an increased ability to absorb water and nutrients under conditions of water deficit. To unravel the molecular mechanism of water-stress tolerance in wheat, we performed RNA-seq analysis on the two genotypes ...
Behnam Derakhshani, Habtamu Ayalew, Kohei Mishina, Tsuyoshi Tanaka, Yoshihiro Kawahara, Hossein Jafary, Youko Oono   +6 more
doaj   +1 more source

Physiological responses of diploid and doubled diploid 'Rangpur' lime under water deficit [PDF]

, 2015
In citrus, the use of rootstocks promotes productivity, improves fruit quality and may confer resistance or tolerance to biotic and abiotic stress. 'Rangpur' lime (Citrus limonia, Osbeck) is one of the most tolerant rootstock to drought and is largely ...
Da Silva Gesteira, Abelmon, Magalhaes De Oliveira, Tahise, Maserti, Bianca Elena, Micheli, Fabienne, Morillon, Raphaël, Navarro, Luis, Ollitrault, Patrick, Talon, Manuel   +7 more
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

When the taps run dry: Water stress and social unrest revisited

Revista UNISCI, 2018
Water stress presents a wide range of concerns that can jeopardize international security. Neo-Malthusians scholars constantly warn of water conflicts, while institutionalists argue that possible water conflicts are the result of poor water distribution ...
Alfonso Sánchez, Guillermo Rylance
doaj   +1 more source

Cytokinins and Water Stress

Biologia plantarum, 2000
It is almost impossible to find a single process in plant life that is not affected by both stress and hormones directly or indirectly. This minireview is focused on the interactions between water stress and cytokinins (CKs). The attention was paid mainly to changes in endogenous CK content and composition under water stress, involvement of CK in plant
J. Pospíšilová, H. Synková, J. Rulcová   +2 more
openaire   +1 more source

Norepinephrine Involvement in the Intermittent Swim Stress-Induced Deficit in Spatial Learning and Memory [PDF]

, 2013
Learning and memory impairments are often caused by stress disorders including depression. The present study investigated the involvement of norepinephrine in the swim stress-induced deficits of spatial learning and memory.
Elgert, Emily
core   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source