Results 121 to 130 of about 8,365,932 (359)

Australia’s water security part 2: water use [PDF]

This report argues that Australia has a need for greater water use efficiency and the identification and utilisation of alternative water resources to avoid potential conflict between users.
Sinéad Lehane
core  

Exploring the link between more negative osmotic potential and ryegrass summer performance [PDF]

, 2018
This paper outlines recent research studying within-population variation in selected New Zealand perennial ryegrass cultivars, for traits related to tolerance of summer moisture deficit.
Dong, W, Lopez, IF, Matthew, C, Nie, M, Wang, Y, Weerarathne, LVY   +5 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Water Retention in a Small Agricultural Catchment and its Potential Improvement by Design of Water Reservoirs – A Case Study of the Bílý Potok Catchment (Czechia)

European Countryside, 2018
Water retention in the landscape is discussed in the context of conservation and improvement of both its productive and non-productive functions. We analysed the retention potential of a small agricultural catchment associated with the Bílý potok brook ...
Doležal Petr, Konečná Jana, Karásek Petr, Podhrázská Jana, Pochop Michal   +4 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Evaluating the impact of drought and water restrictions on agricultural production in irrigated areas through crop water productivity functions and a remote sensing-based evapotranspiration model

Agricultural Water Management
In Mediterranean regions, climate change is leading to reduced precipitation, along with more frequent and severe droughts, and prolonged periods of water scarcity. In this context, as reservoir levels drop dramatically, some irrigated agricultural areas
Joaquim Bellvert, Magí Pamies-Sans, Jaume Casadesús, Joan Girona   +3 more
doaj   +1 more source

Drinking Water Quality Deterioration in Households of Students with High Illness Absenteeism [PDF]

, 2011
Objective: School and household lacked safe drinking water and thus school absenteeism rates were high among students with poor water quality. So we assessed fecal contamination of drinking water in households of students with high illness absenteeism ...
Bhadange, DG, Shirsat, SD, Tambekar, DH
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source