Results 51 to 60 of about 3,611,085 (310)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Applications for Unbounded Convergences in Banach Lattices

open access: yesFractal and Fractional, 2022
Several recent papers investigated unbounded convergences in Banach lattices. The focus of this paper is to apply the results of unbounded convergence to the classical Banach lattice theory from a new perspective.
Zhangjun Wang, Zili Chen
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

On weak convergence of locally periodic functions

open access: yes, 2001
We prove a generalization of the fact that periodic functions converge weakly to the mean value as the oscillation increases. Some convergence questions connected to locally periodic nonlinear boundary value problems are also considered.Comment: arxiv ...
Bensoussan A   +15 more
core   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Weak convergence of a splitting algorithm in Hilbert spaces

open access: yes, 2017
In this paper, we present a splitting algorithm with computational errors for solving common solutions of zero point, fixed point and equilibrium problems.
S. Cho, B. B. Dehaish, X. Qin
semanticscholar   +1 more source

Weak convergence rates of spectral Galerkin approximations for SPDEs with nonlinear diffusion coefficients [PDF]

open access: yesThe Annals of Applied Probability, 2014
Strong convergence rates for (temporal, spatial, and noise) numerical approximations of semilinear stochastic evolution equations (SEEs) with smooth and regular nonlinearities are well understood in the scientific literature.
Daniel Conus   +2 more
semanticscholar   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

On Strong Convergence to Equilibrium for the Boltzmann Equation with Soft Potentials

open access: yes, 2009
The paper concerns $L^1$- convergence to equilibrium for weak solutions of the spatially homogeneous Boltzmann Equation for soft potentials $(-4\le ...
B. Wennberg   +32 more
core   +3 more sources

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