Results 41 to 50 of about 417,817 (243)

Twistors and supertwistors for exceptional field theory [PDF]

, 2015
As a means of examining the section condition and its possible solutions and relaxations, we perform twistor transforms related to versions of exceptional field theory with Minkowski signature.
Cederwall, Martin
core   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Electromagnetic interactions of higher dimensional quantum Hall droplets

, 2005
Using a $W_{N}$-gauge theory to describe electromagnetic interactions of spinless fermions in the lowest Landau level, where the $W_{N}$ transformations are nonlinear realizations of U(1) gauge transformations, we construct the effective action ...
Behr, Bernevig, Bernevig, Cappelli, Chen, Chen, Dhar, Dhar, Dhar, Dimitra Karabali, Dolan, Donaldson, Elvang, Fabinger, Frohlich, Hu, Iso, Iso, Karabali, Karabali, Karabali, Kato, Kimura, Lee, Madore, Madore, Meng, Murakami, Nair, Nair, Nair, Polychronakos, Polychronakos, Sakita, Sakita, Sakita, Seiberg, Shizuya, Sinova, Stone, Stone, Wen, Wunderlich, Zhang, Zhang   +44 more
core   +1 more source

Action based approach to the dynamics of extended bodies in General Relativity [PDF]

, 2003
We present, for the first time, an action principle that gives the equations of motion of an extended body possessing multipole moments in an external gravitational field, in the weak field limit.
JEEVA ANANDAN, Madore J., Mathisson M., NARESH DADHICH, PARAMPREET SINGH   +4 more
core   +4 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Читать далее Scientific and Educational Clusters in Regional Innovative and Investment Capacity [PDF]

AlterEconomics
In the context of modern socio-economic development, the knowledge economy faces two key transformations. First, scientific and educational clusters (universities) are turning from self-governing entities to active players driving innovation and ...
Antonina S. Golubeva, Kristina I. Kanunnikova, Alexander R. Volkov   +2 more
doaj   +1 more source

Gauge Invariance in Simplicial Gravity [PDF]

, 1996
The issue of local gauge invariance in the simplicial lattice formulation of gravity is examined. We exhibit explicitly, both in the weak field expansion about flat space, and subsequently for arbitrarily triangulated background manifolds, the exact ...
Agishtein, Agishtein, Agishtein, Agishtein, Ambjorn, Ambjorn, Ambjorn, Ambjorn, Anselmi, Bander, Bander, Bander, Beirl, Beirl, Beirl, Beirl, Berg, Berg, Bhanot, Bialas, Bock, Boulatov, Cheeger, Cheeger, Christ, Christ, Christ, David, David, De Alfaro, De Alfaro, De Alfaro, de Bakker, de Bakker, DeWitt, DeWitt, DeWitt, Distler, Donoghue, Drouffe, Espriu, Espriu, Fadeev, Fadeev, Feinberg, Forster, Forster, Friedberg, Fujikawa, Fujikawa, Fujikawa, Fujikawa, Gardner, Gross, Hamber, Hamber, Hamber, Hamber, Hamber, Hamber, Hamber, Hamber, Hamber, Hamber, Hamber, Hamber, Hamber, Hamber, Hamber, Hamber, Hamber, Hamber, Hamber, Hamber, Hartle, Hartle, Hartle, Hawking, Herbert W. Hamber, Holm, Holm, Itzykson, Janke, Jevicki, Jevicki, Kawai, Kazakov, Knizhnik, Koibuchi, Koibuchi, Koibuchi, Konopleva, Lee, Lund, Menotti, Menotti, Misner, Modanese, Modanese, Muzinich, Nakajima, Nishimura, Polyakov, Polyakov, Polyakov, Regge, Ren, Ren, Roček, Roček, Ruth M. Williams, Tabor, Varsted, Varsted, Vekić, Vekić, Vekić, Vekić, Veltman, Williams, Williams   +120 more
core   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source