Results 71 to 80 of about 3,954,992 (288)

The Weak Bruhat Order and Separable Permutations [PDF]

open access: yes, 2010
In this paper we consider the rank generating function of a separable permutation $\pi$ in the weak Bruhat order on the two intervals $[\text{id}, \pi]$ and $[\pi, w_0]$, where $w_0 = n,(n-1),..., 1$. We show a surprising result that the product of these
Wei, Fan
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Order ideals in weak subposets of Young's lattice and associated unimodality conjectures [PDF]

open access: yes, 2004
The k-Young lattice Y^k is a weak subposet of the Young lattice containing partitions whose first part is bounded by an integer k>0. The Y^k poset was introduced in connection with generalized Schur functions and later shown to be isomorphic to the weak ...
Lapointe, Luc, Morse, Jennifer
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Effects of Second-Order Matched Stochastic Resonance for Weak Signal Detection

open access: yesIEEE Access, 2018
Weak signal detection via stochastic resonance (SR) has attracted considerable attention in a wide range of research fields, especially under heavy background noise circumstances.
Haitao Dong   +3 more
doaj   +1 more source

Weak Gravitational Lensing in Fourth Order Gravity

open access: yes, 2011
For a general class of analytic $f(R,R_{\alpha\beta}R^{\alpha\beta},R_{\alpha\beta\gamma\delta}R^{\alpha\beta\gamma\delta})$ we discuss the gravitational lensing in the Newtonian Limit of theory.
Stabile, A., Stabile, An.
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Characterizations of the Weak Bivariate Failure Rate Order and Bivariate IFR Aging Class

open access: yesJournal of Mathematics, 2022
In this paper, two characterizations of the weak bivariate failure rate order over the bivariate Laplace transform order of two-dimensional residual lifetimes are given.
M. Kayid
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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